Coats' Disease

Wise, George N.; Horava, Alexander

doi:10.1016/0002-9394(63)91295-9

Cited by 19 publications

(3 citation statements)

References 6 publications

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“…6 7 14 15 22 A number of different vascular findings have been described involving both the arterial and venous system; the initiating event as well as the earliest changes are not certain. Reese re-emphasised the concept that both Leber and Coats probably recognised—namely, that multiple peripheral retinal aneurysms were an early sign of the disease.…”

Section: Discussionmentioning

confidence: 99%

Coats' syndrome: long term follow up

Char

2000

British Journal of Ophthalmology

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Aim-To increase the understanding of the long term results in pseudoretinoblastoma eyes with infantile Coats' syndrome. Methods-This study design was a retrospective case review. 10 patients were analysed who were initially referred with a diagnosis of retinoblastoma but had Coats' syndrome on the basis of ocular oncological evaluation. Vision, fundus photography, ultrasonography, and computed tomography scans were obtained and evaluated. Changes in vision and retinal status were measured. Results-The initial age at presentation was 2.4 years (range 0.25-4 years). All patients had retinal detachment at diagnosis. Nine of 10 retinas were reattached after various treatments. Reattached retinas had closure of peripheral telangiectasia and visible intraretinal crystals. Vision was dismal. At last follow up (mean 8.8 years), only two patients had 20/400 or better visual acuities. Five eyes had no light perception despite early treatment to reattach the retina. Nine of 10 eyes remain cosmetically acceptable. One patient wore a cosmetic shell. Conclusions-Long term results indicate that these eyes can be salvaged and the retina reattached but the visual outcome is poor. (Br J Ophthalmol 2000;84:37-39)

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Section: Discussionmentioning

confidence: 99%

Coats' syndrome: long term follow up

Char

2000

British Journal of Ophthalmology

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“…8 Wise and Horava likewise occasionally observed chorioretinal anastomoses in fibrotic mounds. 9 In comparison, Chang et al reported that no eyes with fibrotic mounds had hemorrhage under the retinal pigment epithelium, therefore suggesting lack of a connection with the choroid. 12 Recently, our group demonstrated the presence of intraretinal neovascularization associated with a subretinal nodule using light micrographs.…”

Section: Discussionmentioning

confidence: 96%

“…4 Using histopathology and multimodal imaging, our group and others had previously demonstrated that type 3 neovascularization can occur in macular fibrosis. 1,2,[6][7][8][9] In this report, we used optical coherence tomography angiography (OCTA) to examine fibrotic nodules in eyes with Coats disease to further elucidate the role of neovascularization in macular fibrosis.…”

Section: Introductionmentioning

confidence: 99%

An Evaluation of the Microvasculature of Macular Nodules in Coats Disease Using Optical Coherence Tomography Angiography: A Report of 3 Cases

Ong

Hsu

Ponugoti

et al. 2021

Journal of VitreoRetinal Diseases

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Purpose: This work aimed to examine the microvasculature of macular fibrosis in Coats disease. Methods: Three boys (aged 3, 4, and 6 years) with Coats disease (stages 2B to 3A2) and macular fibrotic nodules were imaged using optical coherence tomography angiography (OCTA) on the Spectralis spectral-domain OCT tabletop and investigational portable Spectralis Flex module (version 6.9, Heidelberg Engineering). Results: In 2 eyes, a neovascular complex was observed in the avascular slab on OCTA. This neovascular complex had vessels connected to diving vessels from the superficial vascular complex that traveled through the deep vascular complex to the avascular complex. In the third eye, no neovascular complex was observed on OCTA at presentation, but on subsequent examinations fluorescein leakage was observed and cross-sectional OCTA further confirmed the presence of angiographic flow in the nodule. Conclusions: OCTA demonstrates the presence of type 3 neovascularization in fibrotic nodules in Coats disease.

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Facioscapulohumeral dystrophy associated with hearing loss and coats syndrome

Taylor

Carroll

Smith

et al. 1982

Annals of Neurology

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Two unrelated cases of infantile facioscapulohumeral dystrophy (FSHD) with Coats syndrome of the retina and sensorineural hearing loss are described. Children with otherwise unexplained visual or hearing deficit should be examined for somatic muscle weakness, which may present only as facial weakness. Early recognition of Coats syndrome in children with FSHD may lead to preservation of vision with appropriate therapy.

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Coats' Disease

Cited by 19 publications

References 6 publications

Coats' syndrome: long term follow up

Coats' syndrome: long term follow up

An Evaluation of the Microvasculature of Macular Nodules in Coats Disease Using Optical Coherence Tomography Angiography: A Report of 3 Cases

Facioscapulohumeral dystrophy associated with hearing loss and coats syndrome

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