At Praia Rei CortiS co (PRC), coastal Portugal, we analyzed compound-specific isotopes of plant wax-derived n-alkanes in combination with molecular distribution proxies and C/N ratios to reconstruct hydrologic and environmental change in a mid-Holocene wetland. During this relatively brief segment of the Holocene (6.6-5.4k cal a BP), substantial shifts in the stable hydrogen isotope composition of terrestrially sourced C 29 n-alkanes (dD n-C29 ) record significant multi-decadal changes in precipitation origin and storm trajectory. Wetland formation at PRC occurred during a humid interval (6.6-6.5k cal a BP) with a dominantly tropical precipitation source, likely the result of a persistent negative phase of the North Atlantic Oscillation, which permitted the establishment and dominance of Sphagnum moss. A subsequent decrease in precipitation significantly reduced Sphagnum abundance at PRC, which is evidenced by decreased sedimentary C/N ratios and reduced mid-chain n-alkane abundances. From 5.9 to 5.4k cal a BP, relatively low dD n-C29 values coincide with sand invasion along the Iberian coast and cooling in the North Atlantic. Strong correspondence between dD n-C29 values and the occurrence of ice-rafted debris recorded in deep sea sediment cores during this period illustrate a marked North Atlantic control on the trajectory of mid-latitude storms and precipitation regimes in Iberia.