Coarctation of the aorta in adults: preoperative evaluation with MDCT angiography

Türkvatan, Aysel; Akdur, Pınar Özdemir; Ölçer, Tülay; Cumhur, Turhan

doi:10.4261/1305-3825.dir.2434-08.1

Cited by 12 publications

(13 citation statements)

References 15 publications

(15 reference statements)

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“…The ratio of the aortic diameter at the coarctation site to that at the diaphragm (coarctation site–diaphragm ratio, CDR) was calculated to describe the degree of coarctation. The CoA was identified with a CDR less than 75% [ 2 ]. Patients with CoA were classified into two groups based on the severity of coarctation: mild group (CDR > 50%) and severe group (CDR < 50%) [ 2 ].…”

Section: Methodsmentioning

confidence: 99%

“…The CoA was identified with a CDR less than 75% [ 2 ]. Patients with CoA were classified into two groups based on the severity of coarctation: mild group (CDR > 50%) and severe group (CDR < 50%) [ 2 ]. Given the growth-related changes, aortic diameter was standardized as z-score, the ratio of the aortic diameters over the square root of body surface area (BSA) [ 12 ].…”

Section: Methodsmentioning

confidence: 99%

“…Coarctation of aorta (CoA) is one of the most common congenital heart diseases and covers about 6–8% in live births with congenital heart diseases [ 1 ]. Patients with progressive course may develop aortic dilation and are at risk for aortic diseases, including aortic aneurysm, aortic dissection and aortic rupture, which may induce sudden death [ 2 , 3 ]. In recent years, postoperative progressive aortic dilation among patients with CoA has been frequently reported, but the mechanism remains unclear.…”

Section: Introductionmentioning

confidence: 99%

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Predictors of aortic dilation in patients with coarctation of the aorta: evaluation with dual-source computed tomography

Zhao

Shi

Yang

et al. 2018

BMC Cardiovasc Disord

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BackgroundCoarctation of aorta (CoA) may progressively develop aortic dilation at other site of the aorta and can lead to fatal aortic diseases. We aimed to evaluate the occurrence of aortic dilation and related predictors in patients with CoA using dual-source computed tomography (DSCT).MethodsFifty-three patients with CoA identified by DSCT were retrospectively reviewed. Aortic diameters were measured at six different levels and standardized as z-scores based on the square root of body surface area. Coarctation site–diaphragm ratio (CDR) was used to describe the degree of narrowing. A total of 26 patients were included in mild group (CDR > 50%) and 27 in severe group (CDR < 50%) according to the severity of coarctation. Student’s t-test and Spearman correlation coefficients, univariate and multivariable logistic regression analyses were used to assess the risk factors including age, degree of narrowing and other malformations for aortic dilation.ResultsSevere group had significantly larger z-scores of ascending aorta (2.41 ± 0.39 vs. 2.10 ± 0.57, p < 0.05) and post-coarctation aorta (2.17 ± 0.48 vs. 1.68 ± 0.43, p < 0.001) compared with mild group. Degree of coarctation was associated with the z-scores of the ascending aorta (r = − 0.356, p < 0.05) and post-coarctation aorta (r = − 0.414, p < 0.05). Collateral circulation was related to the z-scores of ascending aorta (r = 0.375, p < 0.05). Increased severity of coarctation was independent predictor of ascending (odds ratio 7.46; 95% CI 1.19–46.76; p < 0.05) and post-coarctation aortic dilation(odds ratio 8.42; 95% CI 1.84–38.56; p < 0.05).ConclusionsAscending and post-coarctation aortic diameters or dilations were both associated with the degree of coarctation. By comprehensively evaluating the aortic diameters and associated malformations including collateral circulation, DSCT can aid in stratification of risk for aortic dilation in patients with CoA.Electronic supplementary materialThe online version of this article (10.1186/s12872-018-0863-8) contains supplementary material, which is available to authorized users.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Predictors of aortic dilation in patients with coarctation of the aorta: evaluation with dual-source computed tomography

Zhao

Shi

Yang

et al. 2018

BMC Cardiovasc Disord

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“…6). Moreover, MDCT can readily detect complications, such as dissection, aneurysm, and rupture (14,15).…”

Section: Aortic Coarctationmentioning

confidence: 99%

Congenital thoracic arterial anomalies in adult: CT overview

Yıldırım

Karabulut²,

Doğan³

et al. 2011

Diagn Interv Radiol

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“…(Figures 1, 2). A radiologist with 10 years’ experience evaluated the data sets for each of the cases [4]. …”

Section: Methodsmentioning

confidence: 99%

Diagnosis of Congenital Coarctation of the Aorta and Accompany Malformations in Infants by Multi-Detector Computed Tomography Angiography and Transthoracic Echocardiography: A Chinese Clinical Study

et al. 2017

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BackgroundThe purpose of this study was to evaluate the utility of multi-detector computed tomography (MDCT) angiography and transthoracic echocardiography (TTE) in the diagnosis of congenital coarctation of the aorta (CoA) and accompanying malformations in infants.Material/MethodsFrom January 2012 and December 2015, we enrolled 68 infants with clinically suspected CoA who underwent MDCT angiography and TTE in our hospital. Surgical correction was conducted to confirm the diagnostic accuracy of both examinations in all patients.ResultsIn this study, the diagnosis of CoA was confirmed infants by surgical results in 55 of 68 infants. The diagnostic accuracy, sensitivity, and specificity of MDCT angiography were 95.6%, 96.4%, and 92.3%, respectively. The diagnostic accuracy, sensitivity, and specificity of TTE were 88.2%, 90.9%, and 76.9%, respectively. There was no significant difference in diagnostic accuracy, sensitivity, and specificity between MDCT angiography and TTE (χ2=2.473, p>0.05, χ2=1.373, p>0.05 and χ2=1.182, p>0.05, respectively). In the diagnosis of concomitant cardiac abnormalities with CoA, the 2 methods also play different roles.ConclusionsMDCT angiography and TTE play different roles in the diagnosis of CoA and accompany malformations. MDCT angiography in the diagnosis of the extra-cardiac vascular malformations is better than TTE, and TTE is superior to MDCT angiography in diagnosing intracardiac malformation. Combined MDCT angiography and TTE is a relatively valuable, reliable, and noninvasive method in the diagnosis of CoA and accompany malformations in infants.

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Coarctation of the aorta in adults: preoperative evaluation with MDCT angiography

Cited by 12 publications

References 15 publications

Predictors of aortic dilation in patients with coarctation of the aorta: evaluation with dual-source computed tomography

Predictors of aortic dilation in patients with coarctation of the aorta: evaluation with dual-source computed tomography

Congenital thoracic arterial anomalies in adult: CT overview

Diagnosis of Congenital Coarctation of the Aorta and Accompany Malformations in Infants by Multi-Detector Computed Tomography Angiography and Transthoracic Echocardiography: A Chinese Clinical Study

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