Coagulopathy management of multiple injured patients – a comprehensive literature review of the European guideline 2019

Traumatic brain injury (TBI), a leading cause of death and poor neurological outcomes in trauma patients, is a primary cause of severe disability among survivors and a major public health burden globally. Optimal haemodynamic management is a keystone of care in avoiding secondary brain injury, and contributes to minimising mortality and morbidity. Although some important progress has been achieved, a paucity of high-quality recommendations still exists. The purpose of this article is to review the current knowledge on TBI-associated haemodynamic tenets, in order to summarise the most important aspects of this heterogeneous and complex field.

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Pathological Background and Clinical Procedures in Oral Surgery Haemostasis Disorders: A Narrative Review

Pulicari

Pellegrini

Scribante

et al. 2023

Applied Sciences

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Haemostasis disorders are serious pathologies that could put dental and surgical procedures at risk as they are associated with postoperative bleeding, which in some circumstances could be prolonged and dangerous for the patient. In-depth knowledge of the problems associated with coagulation pathologies and the suitable specific procedures should be implemented in dental practice. A good awareness of the clinical protocols to be used in these circumstances may help reduce operator stress and increase patient compliance. Collaboration with the haematologist is always recommended to establish an adequate treatment plan, both regarding the administration of therapies that promote haemostasis and for assessing the operative risk. Hereby, we summarize the congenital and hereditary pathologies that lead to haemostasis disorders, which can be found in patients undergoing dental procedures. The purpose of this narrative review is to frame the diseases from a clinical, anamnestic, and etiopathological standpoint, as well as to evaluate an operative approach to the pathology under consideration, with particular attention to anaesthesia manoeuvres and post-surgical haemostasis, to avoid hematoma formation and uncontrolled bleeding which can lead procedure failure up and even death. Of note, it is likewise important to educate the patient about prevention, to keep the oral cavity healthy and avoid invasive procedures, limiting the number of operative sessions.

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Coagulopathy management of multiple injured patients – a comprehensive literature review of the European guideline 2019

Cited by 3 publications

References 167 publications

Independent predictors of mortality for critically ill patients with polytrauma: A single center, retrospective study

Independent predictors of mortality for critically ill patients with polytrauma: A single center, retrospective study

Eight rules for the haemodynamic management of traumatic brain-injured patients

Pathological Background and Clinical Procedures in Oral Surgery Haemostasis Disorders: A Narrative Review

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