Coagulopathy Management in Liver Transplantation

Impact of Preemptive Fibrinogen Concentrate on Transfusion Requirements in Liver Transplantation: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

“…Packed red blood cells (RBCs) are transfused in 20-86% of patients in liver transplantation (LT) (1). A Cochrane review on methods for attenuating blood loss and decreasing transfusion requirements in LT concluded that antifibrinolytic therapy and use of viscoelastic point-of-care testing may potentially reduce blood loss and transfusion requirements, although they pointed out the need for welldesigned randomized trials (2).…”

Intestinal transplantation: The anesthesia perspective

“…FIBTEM can be used to assess clot firmness and then fibrinogen therapy can be titrated [68]. Alternatively, when diffuse bleeding is detected, a plasma fibrinogen value b 1 g/L should be the aim [69].…”

Hemostasis, Disorders of Coagulation and Transfusion in Cirrhosis

“…These include dissection or preanhepaticphase, anhepatic phase, post-reperfusion phase and early post-operative period [25]. In the anhepatic phase, no important surgical blood loss is usually seen because of appropriate clamping of vessels.…”