Coagulopathy and its Correction by Vitamin K in Children with Celiac Disease

Abstract

Background: 25% of children with Celiac disease (CD) have coagulopathy at the time of presentation. Diagnosis of CD involves endoscopy and multiple duodenal biopsies. Risk of bleeding with endoscopy and biopsy is more if there is underlying coagulopathy.Objective: to study the correlation of coagulopathy with grade of histology in CD and to assess the response of a single dose of vitamin K on coagulopathy in children undergoing upper GI endoscopy and duodenal biopsy for CD.