Coagulation tests in future studies: what to use?

Perioperative coagulation management is a complex task that has a significant impact on the perioperative journey of patients. Anaesthesia providers play a critical role in the decision-making on transfusion and/or haemostatic therapy in the surgical setting. Various tests are available in identifying coagulation abnormalities in the perioperative period. While the rapidly available bedside haemoglobin measurements can guide the transfusion of red blood cells, blood product administration is guided by many in vivo and in vitro tests. The introduction of newer anticoagulant medications and the implementation of the modified in vivo coagulation cascade have given a new dimension to the field of perioperative transfusion medicine. A proper understanding of the application and interpretation of the coagulation tests is vital for a good perioperative outcome.

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“…Both TEG ® and ROTEM ® allow the assessment of fibrinogen function using tests such as the Functional fibrinogen and FIBTEM ® . [ 24 ]…”

Section: Viscoelastic Measures Of Coagulationmentioning

confidence: 99%

Coagulation testing in the perioperative period

2014

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Effects of Acute Normovolemic Hemodilution on Blood Coagulation: Comparison between Tests of an In Vivo and an In Vitro Model

Souza

Klamt

Garcia

2010

Brazilian Journal of Anesthesiology

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Souza MAB, Klamt JG, Garcia LV-Effects of Acute Normovolemic Hemodilution on Blood Coagulation: Comparison between Tests of an In Vivo and an In Vivo Models. Background and objectives: Normovolemic hemodilution produces conflicting results on hemostasis, since works differ according to the fluids used, degree of hemodilution, method used to evaluate hemostasis, and the way used to produce hemodilution. The effects of hemodilution on hemostasis can depend on how it is done and whether an in vivo or an in vitro model is used. The objective of this study was to evaluate and compare hemostasis in two different degrees of hemodilution in both models.

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Efeito da hemodiluição normovolêmica aguda na coagulação sanguínea: comparação entre os testes colhidos de um modelo in vivo e de um modelo in vitro

Souza

Klamt

Garcia

2010

Rev. Bras. Anestesiol.

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Summary: Souza MAB, Klamt JG, Garcia LV -Effects of Acute Normovolemic Hemodilution on Blood Coagulation: Comparison between Tests of an In Vivo and an In Vivo Models. Background and objectives:Normovolemic hemodilution produces conflicting results on hemostasis, since works differ according to the fluids used, degree of hemodilution, method used to evaluate hemostasis, and the way used to produce hemodilution. The effects of hemodilution on hemostasis can depend on how it is done and whether an in vivo or an in vitro model is used. The objective of this study was to evaluate and compare hemostasis in two different degrees of hemodilution in both models.

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Coagulation tests in future studies: what to use?

Cited by 3 publications

References 12 publications

Coagulation testing in the perioperative period

Coagulation testing in the perioperative period

Effects of Acute Normovolemic Hemodilution on Blood Coagulation: Comparison between Tests of an In Vivo and an In Vitro Model

Efeito da hemodiluição normovolêmica aguda na coagulação sanguínea: comparação entre os testes colhidos de um modelo in vivo e de um modelo in vitro

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