Coagulation Chemistry

Kazal, Louis A.

doi:10.1016/b978-0-12-657102-8.50012-6

Cited by 4 publications

(1 citation statement)

References 222 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The slower activation process of fibrin formation by the intrinsic mechanism is dependent on circulating coagulation factors. The more rapid activation process of the extrinsic system needs an extravascular factor, tissue factor, to initiate the coagulation process 3 . Factor VII (FVII) has a key role in the initiation of the extrinsic coagulation pathway by forming a complex with the tissue factor.…”

Section: Haemostasismentioning

confidence: 99%

Interaction of physical activity and diet: implications for haemostatic factors

Rauramaa

Väisänen²

1999

Public Health Nutr.

View full text Add to dashboard Cite

Regular moderate intensity physical activity and habitual diet providing no more than one third of energy from fats have been recommended for the prevention of atherosclerotic diseases. The background for these guidelines is the key role of plasma lipids. However, the importance of thrombogenesis in acute myocardial infarction has become obvious during the last decade. Hyperlipidaemia and excess of adipose tissue increase platelet aggregability and blood coagulation, and decrease fibrinolysis. Both regular physical activity and dietary fat reduction decrease blood lipids and body fat thereby diminishing the risk of thrombosis. Currently, data on interactions between physical activity and diet on haemostasis are scarce, and the few studies available have not demonstrated additional effects when these two lifestyle modifications have been combined. This paper is restricted only to studies using controlled randomized design. Regular moderate intensity physical activity as well as diet rich in omega-3 fatty acids decrease platelet aggregability. The effects of regular physical activity on plasma fibrinogen remain contradictory, while the impact of diet is even less clear. Plasminogen activator inhibitor-1, a possible link between insulin resistance syndrome and coronary heart disease, may decrease due to physical training or low fat diet. It can be hypothesized that moderation in physical activity and diet carries a more powerful impact on blood coagulation and fibrinolysis than either lifestyle modification alone. Studies focusing on the interactions of regular moderate physical activity and fat-modified diet are needed in efforts to optimize the preventive actions by lifestyle changes.

show abstract

Section: Haemostasismentioning

confidence: 99%

Interaction of physical activity and diet: implications for haemostatic factors

Rauramaa

Väisänen²

1999

Public Health Nutr.

View full text Add to dashboard Cite

show abstract

Hemolymph Clotting in Insects

Bohn¹

1986

Proceedings in Life Sciences

View full text Add to dashboard Cite

Congenital afibrinogenemia: from etiopathogenesis to challenging clinical management

Stančiaková

Kubisz

Dobrotová

et al. 2016

Expert Review of Hematology

View full text Add to dashboard Cite

The authors provide a summary of currently available literature about afibrinogenemia. They collected the information from the scientific journals dedicated to thrombosis and hemostasis and searched world-wide databases. Expert commentary: The most frequent clinical manifestation of this disorder is mucosal bleeding, but musculoskeletal bleeding pattern, gynecologic and obstetric issues, spontaneous bleeding, episodes provoked by minor injury or any other intervention, and even paradoxical thromboembolic events have been published. Afibrinogenemia is the consequence of mutations of the homozygous or compound heterozygous type in gene FGA, FGB or FGG encoding fibrinogen. Pregnant women with a family history, or with a history of consanguinity ought to be properly counselled. However, primary prophylaxis of bleeding events is not suggested. The article deals with actual information about afibrinogenemia contributing to its early diagnosis and effective treatment, which in many cases requires multidisciplinary approach.

show abstract

Coagulation Chemistry

Cited by 4 publications

References 222 publications

Interaction of physical activity and diet: implications for haemostatic factors

Interaction of physical activity and diet: implications for haemostatic factors

Hemolymph Clotting in Insects

Congenital afibrinogenemia: from etiopathogenesis to challenging clinical management

Contact Info

Product

Resources

About