CO2 surgical laser for treatment of stress urinary incontinence in women: a randomized controlled trial

CO2 laser therapy for management of stress urinary incontinence in women: a systematic review and meta-analysis

“…Supplemental Figure 1 displays a summary of the quality assessment of the RCTs 22,24,27,32 which were assessed according to the Cochrane’s risk of bias tool. All RCTs were judged to have low risk of bias for the domains of random sequence generation, incomplete outcome data, and selective reporting.…”

“…Overall, 15 studies with 700 patients suffering from SUI and treated with CO 2 laser therapy met the included criteria and were analyzed. 18,[22][23][24][25][26][27][28][29][30][31][32][33][34][35] Four studies were RCTs, 22,24,27,32 whereas the remaining nine studies were cohort single-arm investigations. 18,23,25,26,[28][29][30][31][33][34][35] The included studies were conducted from 2018 to 2022 and carried out in various countries including Israel (n = 3), Brazil (n = 2), China (n = 2), Taiwan (n = 2), Australia (n = 1), Slovenia (n = 1), Columbia (n = 1), Poland (n = 1), Spain (n = 1), and Indonesia (n = 1).…”

“…However, the results have been constrained by small sample sizes, varying study designs, different follow-up times, and conflicting outcomes. 18,[22][23][24][25][26][27][28][29][30][31][32][33][34][35] All in all, these study findings on CO 2 laser therapy for SUI have not been systematically and comprehensively summarized through meta-analysis. Conducting such research is of utmost importance as it can provide conclusive insights that effectively guide clinical decision-making.…”

Laser devices for vaginal rejuvenation: effectiveness, regulation and marketing

“…A randomized, multicentred, shamcontrolled clinical trial (n = 101) of a CO 2 laser device for the treatment of stress incontinence did not show any subjective or objective improvement in stress incontinence, or difference in adverse events. 9 In contrast, numerous randomized controlled trials of pelvic floor therapy or surgery have shown benefit for women with stress incontinence. 10 Vaginal laser therapies are offered across Canada, and the 10 most populous cities all have at least 1 provider who offers energy-based vaginal rejuvenation procedures.…”

Instruments au laser pour rajeunissement vaginal : efficacité, réglementation et commercialisation

“…Les études recensées ont fait état d’une faible réduction de l’incontinence de stress; toutefois, les paramètres mesurés étaient généralement subjectifs et les périodes de suivi étaient brèves. Un essai clinique randomisé, multicentrique avec témoins sous intervention simulée ( n = 101) sur un dispositif au laser CO 2 pour le traitement de l’incontinence de stress n’a fait état d’aucune amélioration subjective ou objective de ce symptôme ni d’aucune différence sur le plan des effets indésirables 9 . En revanche, plusieurs essais randomisés et contrôlés sur un traitement axé sur le plancher pelvien ou la chirurgie ont fait état de bienfaits chez des femmes souffrant d’incontinence de stress 10 .…”