CO2 Laser Micromachining of Polymethyl Methacrylate (PMMA): A Review

Vidya, Shrikant; Wattal, Reeta; Singh, Lavepreet; Mathiyalagan, P.

doi:10.1007/978-981-15-8542-5_82

Cited by 10 publications

(5 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Laser ablation, like heated embossing and injection molding, does not require clean‐room facilities. However, poor surface finish quality and bulge formation along the scan route is possible 131,132 . The technique has been utilized to fabricate accordion‐like honeycomb scaffolds for heart cell alignment 133 and multi‐layered valve leaflets with tunable mechanical properties 134 .…”

Section: Strategies For Platform Fabrication and Tissue Constructionmentioning

confidence: 99%

“…However, poor surface finish quality and bulge formation along the scan route is possible. 131,132 The technique has been utilized to fabricate accordion-like honeycomb scaffolds for heart cell alignment 133 and multi-layered valve leaflets with tunable mechanical properties. 134 It has also been used to create microholes in PICO and POMaC microtubes to improve cell permeability and communication.…”

Section: Hot Embossing Injection Molding and Laser Ablationmentioning

confidence: 99%

See 1 more Smart Citation

Advances in cardiac tissue engineering and heart‐on‐a‐chip

Kieda,

Shakeri,

Landau

et al. 2023

J Biomedical Materials Res

View full text Add to dashboard Cite

Recent advances in both cardiac tissue engineering and hearts‐on‐a‐chip are grounded in new biomaterial development as well as the employment of innovative fabrication techniques that enable precise control of the mechanical, electrical, and structural properties of the cardiac tissues being modelled. The elongated structure of cardiomyocytes requires tuning of substrate properties and application of biophysical stimuli to drive its mature phenotype. Landmark advances have already been achieved with induced pluripotent stem cell‐derived cardiac patches that advanced to human testing. Heart‐on‐a‐chip platforms are now commonly used by a number of pharmaceutical and biotechnology companies. Here, we provide an overview of cardiac physiology in order to better define the requirements for functional tissue recapitulation. We then discuss the biomaterials most commonly used in both cardiac tissue engineering and heart‐on‐a‐chip, followed by the discussion of recent representative studies in both fields. We outline significant challenges common to both fields, specifically: scalable tissue fabrication and platform standardization, improving cellular fidelity through effective tissue vascularization, achieving adult tissue maturation, and ultimately developing cryopreservation protocols so that the tissues are available off the shelf.

show abstract

Section: Strategies For Platform Fabrication and Tissue Constructionmentioning

confidence: 99%

Section: Hot Embossing Injection Molding and Laser Ablationmentioning

confidence: 99%

Advances in cardiac tissue engineering and heart‐on‐a‐chip

Kieda,

Shakeri,

Landau

et al. 2023

J Biomedical Materials Res

View full text Add to dashboard Cite

show abstract

“…The laser power as well as the scanning speed value that is used in combination with its value are what define the scan gap characteristic [21][22][23][24][25]. The value of the surface roughness was determined to be at its lowest when the nozzle gap was adjusted at a measurement of 2 mm.…”

Section: Mean and S/n Ratio Surface Roughness Analysismentioning

confidence: 99%

The Effect of Co2 Laser Engrave Parameters on Surface Roughness on Polymethylmethacrylate (Pmma)

Isnin,

Sh Abdul Nasir,

Hemdi

et al. 2023

View full text Add to dashboard Cite

The investigation of the laser engraving process has been the focus of a significant amount of research in the field of laser machines. On the surface of the material, gaps and imperfections will appear as a natural result of the engraving process. It is widely held that the surface texture of a material has a significant impact on the material's mechanical qualities, as well as its functional performance and aesthetic appeal. As a result, the purpose of this study is to investigate the influence that different process parameters have on the PMMA (polymethylmethacrylate) surface during the engraving process. PMMA was used throughout this investigation in the engraving process, which was carried out by a machine equipped with a 40W CO2 laser tube. In order to explore the effect that laser engraving has on materials, a total of 25 separate experiments were carried out in line with the Taguchi design principles. It has been investigated how surface roughness (Ra), as well as total machining time, is affected by the laser power, scanning speed, scan gap, and nozzle distance that are considered to be input factors. According to the findings, the surface roughness of the sample had a value that varied from 0.810 to 5.159 micrometres when measured in terms of distance. The factor that has the greatest influence on the Ra value is the scanning speed, which is followed by the nozzle distance, laser power, and scan gap. On the other hand, the amount of time necessary for the machine to finish engraving on the sample can range anywhere from 58 to 135 seconds, with the scanning speed being the characteristic that has the most influence on this figure.

show abstract

“…Further, the cut profile in conventional laser cutters is only limited to Gaussian-shaped profile or through cuts (Figure 2a) [70]. Formation of bulge along the scan route is another common problem associated with laser cutting technique [71]. Chai et al showed that high thermal resistant thermoplastic polymers, such as polyformaldehyde (POM), can be CO 2 laser cut without formation of bulges and carbide residue, and the channel depth and width are easily adjustable by changing the scan speed and laser energy (Figure 2b) [72].…”

Section: Laser Ablationmentioning

confidence: 99%

The Fabrication and Bonding of Thermoplastic Microfluidics: A Review

et al. 2022

View full text Add to dashboard Cite

Various fields within biomedical engineering have been afforded rapid scientific advancement through the incorporation of microfluidics. As literature surrounding biological systems become more comprehensive and many microfluidic platforms show potential for commercialization, the development of representative fluidic systems has become more intricate. This has brought increased scrutiny of the material properties of microfluidic substrates. Thermoplastics have been highlighted as a promising material, given their material adaptability and commercial compatibility. This review provides a comprehensive discussion surrounding recent developments pertaining to thermoplastic microfluidic device fabrication. Existing and emerging approaches related to both microchannel fabrication and device assembly are highlighted, with consideration toward how specific approaches induce physical and/or chemical properties that are optimally suited for relevant real-world applications.

show abstract

CO2 Laser Micromachining of Polymethyl Methacrylate (PMMA): A Review

Cited by 10 publications

References 21 publications

Advances in cardiac tissue engineering and heart‐on‐a‐chip

Advances in cardiac tissue engineering and heart‐on‐a‐chip

The Effect of Co2 Laser Engrave Parameters on Surface Roughness on Polymethylmethacrylate (Pmma)

The Fabrication and Bonding of Thermoplastic Microfluidics: A Review

Contact Info

Product

Resources

About