Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury.

Abstract

Van Hoose, Patrick, "Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury." (2015). However, following aging the co-treatment was unable to restore aging induced mitochondrial dysfunction. These results demonstrate that in combination the dietary constituents, cLA and nitrite, are able to influence mitochondrial function under non-injury setting and following MI. Overall, this supports a role of mitochondria in the cardioprotective effects mediated by a combination treatment of cLA and nitrite.vii