CO₂ Laser Treatment in 244 Patients With Respiratory Papillomas

Abstract

Frequent and meticulously performed CO(2) laser excisions can achieve significant voice and airway improvement, and some clinical "cures." However, effective antiviral medicines and/or immunologic agents are needed to achieve true cures with elimination of all human papilloma virus 6 and 11 viruses.

British Association of Paediatric Otorhinolaryngology members experience with recurrent respiratory papillomatosis

“…In one department the pulsed dye diode laser is used. The CO 2 laser has stood the test of time as one of the preferred surgical methods but is not without its problems, related to expense, risk of airway fire, delayed and collateral local tissue damage and the potential for HPV DNA particles aerosolization during the procedure [9,10]. The 585 nm pulsed dye laser has been reported as a safer alternative [11].…”

Lung involvement in juvenile onset recurrent respiratory papillomatosis: A systematic review of the literature

“…Six studies explored treatment of laryngeal papillomatosis in their cohort of patients [94,[97][98][99]106,113]. Five studies dealt specifically with tracheo-bronchial and pulmonary involvement [95,108,109,111,112] and were descriptive in nature.…”

Natural History of Adult-Onset Laryngeal Papillomatosis following Multiple Cidofovir Injections

“…Several authors have reported intermediate or long-term results of using C02 laser excision 16 or adjuvant therapies such as interferon alfa-Nl ,'? photodynamic therapy.t'' intralesional mumps vaccine, 19 or indole-Lcarbinol-" (Table 3 16 -2°) .…”