Co-solvent Selection for Supercritical Fluid Extraction of Astaxanthin and Other Carotenoids from Penaeus monodon Waste

Radzali, Shazana Azfar; Baharin, Badlishah Sham; Othman, Rashidi; Markom, Masturah; Rahman, Russly Abdul

doi:10.5650/jos.ess13184

Cited by 54 publications

(30 citation statements)

References 37 publications

(29 reference statements)

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“…Table 2 , Table 3 , Table 4 and Table 5 list the best extraction conditions for marine carotenoids using MAE [ 43 , 114 ], UAE [ 53 , 60 , 61 , 65 , 114 , 115 , 116 , 117 ], SFE [ 53 , 56 , 57 , 60 , 61 , 62 , 69 , 70 , 100 , 116 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 ] and PLE [ 65 , 69 , 70 , 115 , 129 , 130 , 131 , 132 ]. When several extraction conditions were tested, the best ones are marked with a symbol (§).…”

Section: Most Common Marine Compounds Obtained By Alternative Extrmentioning

confidence: 99%

Alternative and Efficient Extraction Methods for Marine-Derived Compounds

et al. 2015

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Marine ecosystems cover more than 70% of the globe’s surface. These habitats are occupied by a great diversity of marine organisms that produce highly structural diverse metabolites as a defense mechanism. In the last decades, these metabolites have been extracted and isolated in order to test them in different bioassays and assess their potential to fight human diseases. Since traditional extraction techniques are both solvent- and time-consuming, this review emphasizes alternative extraction techniques, such as supercritical fluid extraction, pressurized solvent extraction, microwave-assisted extraction, ultrasound-assisted extraction, pulsed electric field-assisted extraction, enzyme-assisted extraction, and extraction with switchable solvents and ionic liquids, applied in the search for marine compounds. Only studies published in the 21st century are considered.

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Section: Most Common Marine Compounds Obtained By Alternative Extrmentioning

confidence: 99%

Alternative and Efficient Extraction Methods for Marine-Derived Compounds

et al. 2015

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“…Astaxanthin (3,3 -dihydroxy-β,β'-carotene-4,4 -dione, AST) is a chiral xanthophyll that plays essential photochemical and physiological roles in animals, plants and microorganisms [1]. This carotenoid pigment has been found in most crustaceans, microalgae, and microorganisms [2]. Compared to synthetic AST, natural AST extracted from bioproducts, such as enzymatic hydrolysis of shrimp waste, supercritical fluid extraction from Parapeneus longirostris, etc.…”

Section: Introductionmentioning

confidence: 99%

The Astaxanthin Aggregation Pattern Greatly Influences Its Antioxidant Activity: A Comparative Study in Caco-2 Cells

Dai

Yang

et al. 2020

Antioxidants

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Astaxanthin is an excellent antioxidant that can form unstable aggregates in biological or artificial systems. The changes of astaxanthin properties caused by molecular aggregation have gained much attention recently. Here, water-dispersible astaxanthin H- and J-aggregates were fabricated and stabilized by a natural DNA/chitosan nanocomplex (respectively noted as H-ADC and J-ADC), as evidenced by ultraviolet and visible spectrophotometry, Fourier transform infrared spectroscopy, and Raman spectroscopy. Compared with J-ADC, H-ADC with equivalent astaxanthin loading capacity and encapsulation efficiency showed smaller particle size and similar zeta potential. To explore the antioxidant differences between astaxanthin H- and J-aggregates, H-ADC and J-ADC were subjected to H2O2-pretreated Caco-2 cells. Compared with astaxanthin monomers and J-aggregates, H-aggregates showed a better cytoprotective effect by promoting scavenging of intracellular reactive oxygen species. Furthermore, in vitro 1,1-diphenyl-2-picrylhydrazyl and hydroxyl free radical scavenging studies confirmed a higher efficiency of H-aggregates than J-aggregates or astaxanthin monomers. These findings give inspiration to the precise design of carotenoid aggregates for efficient utilization.

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“…It exhibits powerful anti-oxidant activity compared to that of other carotenoids, such as canthaxanthin, lutein, lycopene, vitamin E, α-carotene, and β-carotene [14]. ATX can effectively scavenge intracellular free radicals and destroy peroxide chain reactions, thereby protecting cell and biological membranes from oxidative damage [15].…”

Section: Introductionmentioning

confidence: 99%

Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis

Xue

Han

et al. 2017

Stem Cell Res Ther

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BackgroundThe hematopoietic system is especially sensitive to total body irradiation (TBI), and myelosuppression is one of the major effects of TBI. Astaxanthin (ATX) is a powerful natural anti-oxidant with low toxicity. In this study, the effect of ATX on hematopoietic system injury after TBI was investigated.MethodsFlow cytometry was used to detect the proportion of hematopoietic progenitor cells (HPCs) and hematopoietic stem cells (HSCs), the level of intracellular reactive oxygen species (ROS), expression of cytochrome C, cell apoptosis, and NRF2-related proteins. Immunofluorescence staining was used to detect Nrf2 translocation. Western blot analysis was used to evaluate the expression of apoptotic-related proteins. Enzymatic activities assay kits were used to analyze SOD2, CAT, and GPX1 activities.ResultsCompared with the TBI group, ATX can improve radiation-induced skewed differentiation of peripheral blood cells and accelerate hematopoietic self-renewal and regeneration. The radio-protective effect of ATX is probably attributable to the scavenging of ROS and the reduction of cell apoptosis. These changes were associated with increased activation of Nrf2 and downstream anti-oxidative proteins, and regulation of apoptotic-related proteins.ConclusionsThis study suggests that ATX could be used as a potent therapeutic agent to protect the hematopoietic system against TBI-induced bone marrow suppression.

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Co-solvent Selection for Supercritical Fluid Extraction of Astaxanthin and Other Carotenoids from Penaeus monodon Waste

Cited by 54 publications

References 37 publications

Alternative and Efficient Extraction Methods for Marine-Derived Compounds

Alternative and Efficient Extraction Methods for Marine-Derived Compounds

The Astaxanthin Aggregation Pattern Greatly Influences Its Antioxidant Activity: A Comparative Study in Caco-2 Cells

Astaxanthin attenuates total body irradiation-induced hematopoietic system injury in mice via inhibition of oxidative stress and apoptosis

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