Co-Relation between Vitamin D Levels and Hamilton Depression Scores in Patients with Depression

Husain, Karrar

doi:10.18535/jmscr/v5i7.200

JMSCR

2017

DOI: 10.18535/jmscr/v5i7.200

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Co-Relation between Vitamin D Levels and Hamilton Depression Scores in Patients with Depression

Karrar Husain¹

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2023

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Cited by 1 publication

References 12 publications

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Vitamin D levels and depression in type 2 diabetes mellitus patients: a cross-sectional study

Putranto,

Adhiatma,

Tarigan

et al. 2023

Med J Indones

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BACKGROUND The prevalence of type 2 diabetes mellitus (T2DM) is increasing and commonly accompanied by comorbidities, such as depression. Vitamin D levels have been associated with T2DM and depression although the mechanism is uncertain. This study aimed to compare vitamin D levels between patients with T2DM with and without depression in the Indonesian community, where such research is rare. METHODS This cross-sectional study was conducted at Cipto Mangunkusumo Hospital. The participants who met the inclusion criteria on an outpatient basis were screened for depression using the Beck Depression Inventory-II (BDI-II) questionnaire and then divided into 2 groups: patients with T2DM with (BDI-II ≥14) and without (BDI-II <14) depression. Both groups were examined for vitamin D levels using the ELISA method, and an analysis of the mean difference between both groups was performed. RESULTS Of 60 patients, 23 (38%) experienced depression. The median vitamin D levels were 21.8 ng/ml (IQR 14.9–26.6) in the depression group and 26.5 ng/ml (IQR 23.96–34.08) in the non-depression group (p = 0.001). After performing multivariate analysis with confounding variables, the adjusted OR of variables (sex, sun exposure score, and body mass index) was 1.123 (95% CI: 1.003–1.259; p = 0.045). CONCLUSIONS Vitamin D levels were significantly lower in patients with T2DM with depression. Future studies should be carried out to determine the benefits of vitamin D supplementation in patients with T2DM with depression and their pathophysiology.

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Vitamin D levels and depression in type 2 diabetes mellitus patients: a cross-sectional study

Putranto,

Adhiatma,

Tarigan

et al. 2023

Med J Indones

View full text Add to dashboard Cite

show abstract

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Co-Relation between Vitamin D Levels and Hamilton Depression Scores in Patients with Depression

Cited by 1 publication

References 12 publications

Vitamin D levels and depression in type 2 diabetes mellitus patients: a cross-sectional study

Vitamin D levels and depression in type 2 diabetes mellitus patients: a cross-sectional study

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