Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level

Hakim, Abdul; Rahman, Mahmuder; Begum, Morium

doi:10.11648/j.ajbls.20210905.17

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“…In the present study, plasma glucose levels in cases are lower than controls, which is similar to Lakra et al study [27]. Our study showed a significant negative correlation between severity of HIE and hypoglycemia similar to Abdul Hakim et alstudy [28]. In our study and in the literature, cord blood serum levels of sodium, potassium, calcium and glucose were the best indicators to assess (HIE) asphyxia severity [29].…”

Section: Table (4)supporting

confidence: 91%

Serum Electrolytes and Glucose Levels in Neonates with Perinatal Asphyxia

2022

Al-Azhar University Journal of Virus Researches and Studies

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Hypoxia, hypercarbia, and acidosis during perinatal period is called perinatal asphyxia which cause hypoxic-ischemic damage of tissues and electrolytes disturbances which may be the cause of perinatal morbidity and mortality. The aim of this study was to determine the serum electrolytes (Na, K, Ca, Mg) and plasma glucose levels in neonates with perinatal asphyxia and to determine their correlation with birth asphyxia severity. 100 neonates were divided into two groups (50 cases and 50 controls) based on the Apgar score after baby delivery. The cord blood serum sodium, potassium, calcium, and glucose levels were estimated in both two groups by independent t-test and Mann-Whitney U test using R software version 3.6.0. The serum electrolyte levels were correlated with hypoxic-ischemic encephalopathy stages. Using Spearman correlation. A statistically significant difference was found between the two groups in serum sodium, calcium, potassium and glucose levels (P < 0.05). A significant negative linear correlation was found between serum sodium, calcium, and glucose lvels and hypoxic-ischemic encephalopathy stages. A significant positive linear correlation was found between serum potassium level and hypoxic-ischemic encephalopathy stages. Hyponatremia, hypocalcemia, and hypoglycemia were detected in asphyxiated neonates and were correlated with severity of asphyxia. So, cord blood serum electrolytes and glucose estimation at high-risk neonates would be used for perinatal asphyxia early diagnosis and severity assessment.

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Section: Table (4)supporting

confidence: 91%

Serum Electrolytes and Glucose Levels in Neonates with Perinatal Asphyxia

2022

Al-Azhar University Journal of Virus Researches and Studies

View full text Add to dashboard Cite

show abstract

Co-relation Between Perinatal Asphyxia with Hypoxic Ischemic Encephalopathy (PNA with HIE) and Blood Sugar Level

Cited by 1 publication

References 0 publications

Serum Electrolytes and Glucose Levels in Neonates with Perinatal Asphyxia

Serum Electrolytes and Glucose Levels in Neonates with Perinatal Asphyxia

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