Co-occurring mood disorders among hospitalized patients and risk for subsequent medical hospitalization

Daratha, Kenn B.; Barbosa‐Leiker, Celestina; Burley, Mason; Short, Robert; Layton, Matthew E.; McPherson, Sterling; Dyck, Dennis G.; McFarland, Bentson H.

doi:10.1016/j.genhosppsych.2012.05.001

Cited by 24 publications

(26 citation statements)

References 17 publications

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“…The findings support prior studies documenting the relationship between comorbid SMI diagnoses and rehospitalization [10,13,15,17] and expand this work by highlighting poor health outcomes among persons with a comorbid SMI diagnosis in a population of patients having heterogeneous medical needs. Hospitalized patients with a comorbid SMI diagnosis likely face a complex array of barriers to quality health care including limited access to transitional support postdischarge, community-based care options, and integrated health and behavioral health care [20,21].…”

Section: Current Findingssupporting

confidence: 84%

“…As such, this study operationally defined SMI to encompass comorbid diagnoses of schizophrenia, bipolar disorder and major depression. This definition of SMI has also been used in other studies examining SMI and subsequent medical rehospitalization [17,18]. Using a 12-month look-back from the index hospitalization, we identified patients who had a comorbid SMI diagnosis using the Agency for Healthcare Research and Quality multilevel clinical classification system (CCS) and included those with a diagnosis of CCS 5.8.1-bipolar disorders [International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes: 296.00-296.99], CCS 5.10-schizophrenia and other psychotic disorders (ICD-9-CM codes: 293.81, 293.82, 295.01-295.95, 29,700.0-298.0) and CCS 5.8.2-major depressive disorder (ICD-9 codes: 296.20-296.36) [6], yielding 70,858 without a comorbid SMI diagnosis and 3221 patients with a comorbid SMI diagnosis.…”

Section: Construction Of Serious Mental Illness Rehospitalization Anmentioning

confidence: 99%

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Examining the impact of comorbid serious mental illness on rehospitalization among medical and surgical inpatients

Hanrahan

Bressi

Marcus

et al. 2016

General Hospital Psychiatry

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Section: Current Findingssupporting

confidence: 84%

Section: Construction Of Serious Mental Illness Rehospitalization Anmentioning

confidence: 99%

Examining the impact of comorbid serious mental illness on rehospitalization among medical and surgical inpatients

Hanrahan

Bressi

Marcus

et al. 2016

General Hospital Psychiatry

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“…The findings support most of previous studies [5,22,38,44] for medical cohort, but conflict with previous literatures which claimed that there was no significant association between comorbid SMI and rehospitalization for surgical inpatients [28,45]. The high odds of 30-day rehospitalization among medical and surgical patients can be explained by a poor quality health care due to limited access to transitional support postdischarge, community-based care options, and integrated health and behavioral health care [46,47].…”

Section: Aim 2: Analysis Of National Readmissions With Comorbid Smisupporting

confidence: 53%

“…As such, this study operationally defined SMI to encompass comorbid diagnoses of schizophrenia, bipolar disorder, and major depression. This definition of SMI has also been used in other studies examining SMI and subsequent medical readmissions [28,38,39].…”

Section: Aim 2 Analysis: National Readmissions With Comorbid Smimentioning

confidence: 99%

Detecting cause of readmission : a big data analytics approach

Wang¹

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“…Serious mental illness (SMI, including schizophrenia and mood disorders) is also associated with an increased risk of repeated hospitalization [7,8,9,10]. Mental illness is associated with all-cause mortality, cardiovascular hospitalizations and death in people receiving hemodialysis [11].…”

Section: Introductionmentioning

confidence: 99%

Association of Co-Occurring Serious Mental Illness with Emergency Hospitalization in People with Chronic Kidney Disease

McPherson¹,

Barbosa‐Leiker²,

Daratha

et al. 2014

Am J Nephrol

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Background/Aims: Chronic kidney disease (CKD) and serious mental illness (SMI) are both associated with an increased risk for repeated hospitalization. The objective of this study was to determine if co-occurring SMI exacerbates the risk for subsequent hospitalization, particularly through the emergency department (ED), among people with CKD. Methods: People hospitalized in Washington State from April 2006 to December 2008 were separated into cohorts with diagnoses of CKD (n = 31,166), SMI (defined by schizophrenia and/or mood disorder; n = 20,167) or CKD with co-occurring SMI (n = 717), and a reference cohort without either diagnosis (n = 548,532). Main outcomes were rehospitalization for condition(s) other than mental illness: (1) through the ED; (2) any admission, and (3) admission resulting in death. Cox regression was used to analyze time to main outcomes controlling for prespecified covariates associated with rehospitalization. Results: The risk of rehospitalization via the ED was increased for people with CKD (hazard ratio, HR = 1.24, 95% confidence interval, CI = 1.21-1.28, p < 0.001) and co-occurring SMI (HR = 1.33, 95% CI = 1.29-1.38, p < 0.001) cohorts, but was significantly greater in the combined cohort (HR = 1.55, 95% CI = 1.40-1.73, p < 0.001). Similarly, the risk of any rehospitalization was increased for CKD (HR = 1.21, 95% CI = 1.17-1.25, p < 0.001) and co-occurring SMI (HR = 1.14, 95% CI = 1.11-1.17, p < 0.001) cohorts, while a significantly greater risk was observed for the combined cohort (HR = 1.36, 95% CI = 1.24-1.48, p < 0.001). The risk of rehospitalization resulting in death was not significantly increased in the combined cohort. Conclusion: In people with CKD, co-occurring SMI increased the risk of experiencing rehospitalization, particularly through the ED. Studies of strategies to address SMI in the CKD population are needed to mitigate the risk of repeat hospital admissions.

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Co-occurring mood disorders among hospitalized patients and risk for subsequent medical hospitalization

Cited by 24 publications

References 17 publications

Examining the impact of comorbid serious mental illness on rehospitalization among medical and surgical inpatients

Examining the impact of comorbid serious mental illness on rehospitalization among medical and surgical inpatients

Detecting cause of readmission : a big data analytics approach

Association of Co-Occurring Serious Mental Illness with Emergency Hospitalization in People with Chronic Kidney Disease

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