Co-morbidity of depression and epilepsy in Jimma University specialized hospital, Southwest Ethiopia

Tsegabrhan, Hagos; Negash, Alemayehu; Tesfay, Kenfe; Abera, Mubarek

doi:10.4103/0028-3886.149391

Cited by 33 publications

(30 citation statements)

References 22 publications

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“…People who had side effects of medication and frequent seizure were found to have depression and anxiety as compared to people who had no side effects of medication and no seizure. This finding was consistent with many previous studies [ 9 , 24 ].…”

Section: Discussionsupporting

confidence: 94%

Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia

et al. 2015

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BackgroundAlthough depression and anxiety disorders are very common in people with epilepsy; there are no studies that assessed the magnitude and associated factors among epileptic people in Ethiopia. Therefore, this study determined prevalence and associated factors of depression and anxiety disorders in people with epilepsy.MethodAn institution based cross-sectional study was conducted from April to May, 2013, among 423 people with epilepsy from the outpatient department of Amanuel Mental Specialized Hospital. Depression and anxiety were assessed using the Hospital Anxiety and Depression Scale. Logistic regression analysis was used to assess predictors of depression and anxiety.ResultsThe prevalence of anxiety and depression among epileptic people were 33.5 and 32.8 %, respectively. Monthly income, frequency of seizure and side effects of anti convulsants were found to be significantly associated with both depression and anxiety. Being divorced/widowed was associated with anxiety while using poly-therapy of anti convulsants, perceived stigma, and inability to read or write were associated with depression.ConclusionThe prevalence of co-morbid anxiety and depression was found to be high among people with epilepsy. Early identification of co-morbid depression and anxiety in people with epilepsy and managing epilepsy to become seizure free should be of great concern for health care providers.

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Section: Discussionsupporting

confidence: 94%

Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia

et al. 2015

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“…This is evidenced in the previous community-based study in Ethiopia showed that providing a high level of psychological support protect the individuals from developing common mental illness by 50% [47]. Frequent seizure attacks were associated with common mental illness which is consistent with other studies [48][49][50][51]. Many epilepsy patients become fearful when they have seizure attacks in public place: one of the most awful things for epilepsy patients, felt ashamed about their unpredictable seizure attacks may be associated with socially unaccepted sign like incontinence of feces, urine, jerking movements, bite of tongue or cheek may occur and bloody saliva may come from the mouth.…”

Section: Discussionsupporting

confidence: 89%

Common mental illness among epilepsy patients in Bahir Dar city, Ethiopia: A cross-sectional study

et al. 2020

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Background Common mental illness has a substantial impact on seizure control and negatively affects the overall quality of life among individuals with epilepsy. However, there is a dearth of studies that examined the associated factors of common mental illness among epilepsy patients in Ethiopia, particularly in the study area. This study aimed to assess the magnitude and factors associated with common mental disorders in epilepsy patients who attended government health institutions in Bahir Dar city, Ethiopia. Method Health institution based cross-sectional study was conducted using a systematic sampling technique among people living with epilepsy in Bahir Dar City Administration. Common mental illness was assessed using a self-reporting questionnaire and a semi-structured questionnaire was employed to collect data on socio-demographic and clinical related characteristics. Data were analyzed using descriptive statistics, univariate logistic regression, and multivariable logistic regression. Results The magnitude of comorbid common mental illness among people living with epilepsy was found 35.4%. High magnitude of common mental illness was reported among females (39.9%) when compared to males (32.3%). The most prevalent common mental disorders symptoms include being worried, unhappy feeling, trouble thinking clearly, and difficult to enjoy daily activities. Family history of epilepsy, frequent seizures attacks, side effects of antiepileptic drugs, lack of social support and not adherent to antiepileptic drugs were factors associated with common mental illness. Conclusions Common mental illness was found to be prevalent among people living with epilepsy. Therefore, it is recommended that great attention should be given to mental illness besides controlling seizure attacks.

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“…The prevalence of depression among PWE in this resource limited setting using the primary care validated cut-off (70.8%) was also higher than the general population depression prevalence (28.8%) using the same validated cut-off (5 or more) [38]. This prevalence of depression was also higher than the prevalence that is reported in the institution based studies from Ethiopia [7–9]. Various explanations have been proposed to explain the elevated levels of depression in epilepsy; (1) underlying structural brain disease, (2) damage related to uncontrolled seizures, and (3) psychosocial impact of the stigma and disability associated with epilepsy [6].…”

Section: Discussionmentioning

confidence: 73%

“…Hospital based studies conducted in Ethiopia have shown that the prevalence of depression is high among people with epilepsy [7–9]. Comorbid psychiatric disorders, such as depression, have a substantial negative impact on quality of life [10–12] and are important risk factors for suicidal behaviours [13].…”

Section: Introductionmentioning

confidence: 99%

Help seeking and suicidality among people with epilepsy in a rural low income country setting: cross-sectional survey

Tsigebrhan

Hanlon

Medhin

et al. 2017

Int J Ment Health Syst

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BackgroundsEpilepsy is a serious neurological disorder associated with a high level of psychiatric comorbidity. Suicidality is a recognised complication of epilepsy. As part of developing an integrated service for people with epilepsy (PWE) and priority psychiatric disorders within primary care, a cross-sectional study was conducted in a rural district in Ethiopia to investigate patterns of help-seeking, suicidality and the association with duration of untreated epilepsy (DUE) among PWE.MethodsCases were identified through community key informants and diagnosis was confirmed by trained primary care clinicians. Severity of epilepsy, depression and suicidality were assessed using standardised methods. Multivariable regression analysis was used to test the hypothesis that suicidality was associated with DUE.ResultsThe majority of PWE sought help from both religious and biomedical healing centres. The lifetime treatment gap for biomedical care was 26.9%, with a 12 month treatment gap of 56.7%. Close to one-third (29.9%) of participants reported using traditional and cultural healing practices. Nearly one-third (30.2%) of participants reported suicidality (suicidal ideation, plan or attempt) in the previous 1 year. The median (IQR) DUE was 24 months (4–72). There was no association between DUE and suicidality. In the multivariable model, being married [odds ratio (OR) 2.81, 95% CI 1.22, 6.46], increased depressive symptoms (OR 1.17, 95% CI 1.10, 1.26) and perceived poorer wealth relative to others (OR 2.67, 95% CI 1.07, 6.68) were associated independently with suicidality.ConclusionIn this study, PWE sought help from both biomedical and religious healing centres. Suicidality and depression have a high prevalence in PWE in this setting. Integrated mental and neurological health care within primary care is needed for improved holistic management of epilepsy.

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Co-morbidity of depression and epilepsy in Jimma University specialized hospital, Southwest Ethiopia

Abstract: In this study, depression was found to be highly prevalent. Early recognition and treatment of depression through routine screening and assessment of PWE should become an essential part of diagnosis and treatment protocol.

Cited by 33 publications

References 22 publications

Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia

Depression and anxiety disorder among epileptic people at Amanuel Specialized Mental Hospital, Addis Ababa, Ethiopia

Common mental illness among epilepsy patients in Bahir Dar city, Ethiopia: A cross-sectional study

Help seeking and suicidality among people with epilepsy in a rural low income country setting: cross-sectional survey

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