Co-morbidity, demographic and social factors as predictors of outcome from intensive care: an observational cohort study

Mackay, Andrew; Docking, Robert; Kinsella, John; Booth, M. G.

doi:10.1186/cc8661

Cited by 1 publication

(3 citation statements)

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“…Eight of these articles were published only in abstract or poster-presentation form. 7,9,14,15,17,19,20,22 The 21 studies contained data on a combined cohort of 20,476 patients. Four studies fulfilled all seven domains of the critical appraisal tool, while eight studies had areas of insufficient evidence and nine were deemed to have major flaws ( Table 4).…”

Section: Resultsmentioning

confidence: 99%

“…Gildea (13) 2004 2c 422 Consecutive patients admitted to a medical Non UK centre ICU over a four-year period with diagnosis of cirrhosis. Transplant patients excluded Goutcher (14) 2006 2c 63 All patients with ALD admitted to ICU Abstract only over a five-year period Mackay (15) 2010 2c 500 Prospective case note review of Abstract only 500 admissions to ICU.…”

Section: Review Article Inclusion Criteriamentioning

confidence: 99%

“…Comparing the average admission APACHE II scores from the studies supports this. Mackle' s 16 cohort (unit mortality 56%) had a median APACHE II score of 25 (20-31) while Thomson' s 22 patients (unit mortality 38%) scored a median APACHE II of 16 (13)(14)(15)(16)(17)(18)(19)(20)(21)(22).…”

Section: Review Article Inclusion Criteriamentioning

confidence: 99%

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Mortality of Patients with Alcoholic Liver Disease Admitted to Critical Care: A Systematic Review

Flood

Bodenham

Jackson

2012

Journal of the Intensive Care Society

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This review examined the burden of alcohol-related liver disease (ALD) in the intensive care unit, which is increasing, and whether scoring systems can assist in judging prognosis. Embase, Medline and internet databases were searched for relevant articles whose quality was then scored using the Centre for Evidence-Based Medicine's (CEBM) critical appraisal tool. Unit mortality of patients with ALD admitted to intensive care in these studies was between 40–50%. In comparison with liver-specific prognostic scoring, physiological scoring systems discriminated better between survivors and non-survivors. This is likely to be a reflection of the fact that patients with ALD in intensive care tend to die of multi-organ failure rather than isolated acute liver failure.

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