Co-Morbidities and Sex Differences in Long-Term Quality-of-Life Outcomes among Patients with and without Diabetes after Total Knee Replacement: Five-Year Data from Registry Study

Tew, Michelle; Dowsey, Michelle M.; Choong, Annabelle; Choong, Peter; Clarke, Philip

doi:10.3390/jcm9010019

Cited by 8 publications

(6 citation statements)

References 46 publications

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“…Diabetes mellitus was found to related with poor quality of life. Similar to our study results, after total knee replacement surgery, patients with diabetes were found to exhibit poor quality life scores than patients without diabetes (29). Patients with diabetes usually reacts with aggression predisposition which leads to loss of social support, furthermore sleep disorders and mental comorbidity are associated with lower quality of life in patients with diabetes (30).…”

Section: Discussionsupporting

confidence: 87%

The Relation Between Type 2 Diabetes Mellitus, Knee Osteoarthritis and Ultrasonographic Measurement of Femoral Cartilage Thickness

Bakılan

Ortanca

Şahin

et al. 2023

esmj

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Giriş: Bu çalışmanın amacı 1- tip 2 diyabet ile femoral kartilaj kalınlığı ve diz osteoartriti arasındaki ilişkiyi belirlemek, 2- bu ilişki üzerine beden kitle indeksi, abdominal bel çevresi, HbA1c gibi faktörlerin etkisini araştırmaktır. Yöntem: Bu çalışmaya toplam 126 kadın hasta kabul edilerek, hastalar diyabet varlığı (Diyabet grubu) ve yokluğuna (Kontrol grubu) göre iki gruba ayrıldı. Yaş, HbA1c, beden kitle indeksi, abdominal bel çevresi, vizüel analog skala, yürüme hızı, Kısa Form-36, Kellgren Lawrance Skalası ve ultrasonografik distal femoral kartilaj kalınlık ölçümü çalışmanın değişkenleri idi. Bulgular: İki grup arasında femoral kartilaj kalınlığı arasında bir fark saptanmadı, ne HbA1c ne de vücut kitle indeksi ve bel çevresi değerleri her 2 grupta da femoral kartilaj kalınlığı ile korelasyon göstermedi. Kontrol grubunda hem beden kitle indeksi(r=0.422) hem de bel çevresi(r=0.423) Kellgren skorları ile korelasyon gösterdi. Diyabet grubunda ise hem HbA1c(r=0.404), hem de beden kitle indeksi(r=0.696) ile Kellgren skorları arasında korelasyon saptanmakla birlikte, abdominal bel çevresi (r=0.791) ile Kellgren skorları arasındaki korelasyon daha güçlü düzeyde idi. Sonuç: Tip 2 diyabet ve diz osteoartriti arasında güçlü bir ilişki saptanmıştır ancak tip 2 diyabet ile ultrasonografik femoral kartilaj kalınlığı ölçümü arasında bir ilişki saptanmamıştır. Ayrıca tip 2 diyabet ve osteartritin arasındaki ilişkiye, abdominal obezite, HbA1c ve beden kitle indeksinden daha fazla katkı yapıyor görünmektedir.

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Section: Discussionsupporting

confidence: 87%

The Relation Between Type 2 Diabetes Mellitus, Knee Osteoarthritis and Ultrasonographic Measurement of Femoral Cartilage Thickness

Bakılan

Ortanca

Şahin

et al. 2023

esmj

View full text Add to dashboard Cite

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“…In the study by Snell et al 17 , the most common comorbidities were musculoskeletal conditions, such as arthritis in other joints and other musculoskeletal pain, cardiovascular conditions, such as hypertension, and coronary heart disease. Additionally, Tew et al 45 showed that one-fifth of the patients who underwent TKA developed diabetes. Patients with diabetes, especially women, showed a significantly lower QoL than those without diabetes.…”

Section: Discussionmentioning

confidence: 99%

Factors Correlated with the Quality of Life after Total Knee Arthroplasties: A Literature Review

Nursalam,

Mustikasari

et al. 2024

Malays Orthop J

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Introduction Total Knee Arthroplasty (TKA) has been widely reported to improve outcomes and quality of life (QoL) in patients with knee osteoarthritis (KOA), but there are still 15 - 20% of patients still experience pain, physical limitations, and other complications after TKA. Therefore, it is necessary to identify various factors that correlate with QoL from current evidence. The objective is to review the literature on factors that correlate with QoL in patients who underwent TKA. Materials and methods A literature search was conducted on five databases, i.e. ProQuest, CINAHL, Medline, Embase, and Scopus, using the following keywords: total knee arthroplasty (TKA), post-operative, quality of life (QoL), and outcome. There were no restrictions on the research design. Results This review found 14 articles (7 prospective studies and 7 retrospective studies) involving 15,972 patients who underwent TKA, with an age range of 32 - 94 years. All articles reported improvement in QoL after TKA. The review revealed 30 factors, of which 15 factors were significantly correlated with QoL after TKA. The factors were grouped into four types: demographic, socioeconomic, clinical, and psychosocial factors. Conclusion Information regarding factors that correlate with QoL after TKA can be used for directing treatment and discharge planning according to the patient's factors.

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“…Musculoskeletal disorders and injuries that are characterized by sexual dimorphism are not routinely considered by orthopedic surgeons when making treatment decisions [ 25 ]. This is surprising as sex differences in patient-related outcomes and functionality after orthopedic surgery are well described in the literature [ 26 , 27 , 28 , 29 ]. This observation might partly be caused by sex-specific postoperative morbidity and mortality [ 30 , 31 ].…”

Section: Discussionmentioning

confidence: 99%

Male Sex Is Associated with Higher Mortality and Increased Risk for Complications after Surgical Treatment of Proximal Humeral Fractures

Köppe

Katthagen

Rischen

et al. 2021

JCM

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Aims: The best surgical treatment of multi-fragmentary proximal humeral fractures in the elderly is a highly controversial topic. The aim of this study is to assess for sex-related differences regarding mortality and complications after reverse total shoulder arthroplasty (RTSA) and locking plate fixation (LPF). Patients and Methods: All patients from the largest German healthcare insurance (26.5 million policy holders) above the age of 65 years that were treated with LPF or RTSA after a multi-fragmentary proximal humerus fracture between January 2010 and September 2018 were included. Multivariable Cox regression models were used to assess the association of sex with overall survival, major adverse events and surgical complications. Results: A total of 8264 (15%) men and 45,707 (85%) women were followed up for a median time of 52 months. After 8 years, male patients showed significantly higher rates for death (65.8%; 95% CI 63.9–67.5% vs. 51.1%; 95% CI 50.3–51.9%; p < 0.001) and major adverse events (75.5%; 95% CI 73.8–77.1% vs. 61.7%; 95% CI 60.9–62.5%; p < 0.001). With regard to surgical complications, after adjustment of patient risk profiles, there were no differences between females and males after LPF (p > 0.05), whereas men showed a significantly increased risk after RTSA (HR 1.86; 95% CI 1.56–2.22; p < 0.001) with more revision surgeries performed (HR 1.76, 95% CI 1.46–2.12; p < 0.001) compared to women. Conclusion: The male sex is an independent risk factor for death and major adverse events after both LPF and RTSA. An increased risk for surgical complications after RTSA suggests that male patients benefit more from LPF. Sex should be considered before making treatment decisions.

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Co-Morbidities and Sex Differences in Long-Term Quality-of-Life Outcomes among Patients with and without Diabetes after Total Knee Replacement: Five-Year Data from Registry Study

Abstract: Improved understanding of quality-of-life (QoL) outcomes can provide valuable information on intervention effectiveness and guide better patient care.

Cited by 8 publications

References 46 publications

The Relation Between Type 2 Diabetes Mellitus, Knee Osteoarthritis and Ultrasonographic Measurement of Femoral Cartilage Thickness

The Relation Between Type 2 Diabetes Mellitus, Knee Osteoarthritis and Ultrasonographic Measurement of Femoral Cartilage Thickness

Factors Correlated with the Quality of Life after Total Knee Arthroplasties: A Literature Review

Male Sex Is Associated with Higher Mortality and Increased Risk for Complications after Surgical Treatment of Proximal Humeral Fractures

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