Co-infection with bacterial and fungal endocarditis in neonate and successful medical treatment

Tahazzul, Mohammad; Singh, Shalini; Sharma, Abhinav; Khan, Mohammad W.

doi:10.1016/j.cegh.2012.12.002

Cited by 3 publications

(2 citation statements)

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“…The main predisposing factor in children and adults is cardiac disease whereas the immunity of prematurity [4], invasive procedures, and catheter insertion are the main predisposing factors during the neonatal period [5][6][7]. Additionally, other predisposing factors such as prolonged use of wide-spectrum antibiotics and intestinal surgery also exist in fungal endocarditis, a rare complication of systemic Candida infections [8].…”

Section: Discussionmentioning

confidence: 99%

Eustachian Valve Fungal Endocarditis in Neonate

Ap¹,

Yavuz²,

Karatekın³

2015

JCR

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Abstract:Infective endocarditis remains a significant cause of mortality and morbidity, particularly in the neonatal intensive care unit. A mass of 6x9 mm in size was found on the Eustachian valve during Candida sepsis in a patient born in the 26 th gestational week with birth weight of 1020 grams for threatened preterm labor. The treatment of the patient was switched to caspofungin and voriconazole because of continuing growth of Candida in the blood culture, although it was sensitive to amphotericin B in vitro. The mass on the Eustachian valve disappeared following six weeks of treatment with caspofungin. The patient was discharged on the 88 th post-natal day. We report herein on the first case of neonatal fungal endocarditis in the newborn involving Eustachian valve.

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