Co-Infection of Leishmania (Viannia) braziliensis and HIV: Report of a Case of Mucosal Leishmaniasis in Cochabamba, Bolivia

Abstract

Abstract. We describe the first case of Leishmania/ HIV co-infection reported in Bolivia. Initially hospitalized with a diagnosis of pneumonia and bronchitis, the patient had numerous cutaneous and mucosal lesions caused by Leishmania ( Viannia ) braziliensis. The patient was also diagnosed as severely immunocompromised because of HIV infection.

Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence

“…Patients with suppressed immune systems: ATL infection is emerging as a result of immunosuppression, and HIV is the most common cause 62,[75][76][77][78][79][80][81][82][83][84][85][86][87][88] . Bone marrow or solid organ transplantation [89][90][91][92][93][94][95] and therapy with immunosuppressive or biologic drugs [96][97][98] also have been associated with the appearance of ATL.…”

“…HIV patients had a higher rate of recurrence or reinfection and a lower rate of recovery after pentamidine treatment 80 . In Bolivia, amphotericin deoxycholate was used for 80 days to treat HIV-infected patients with CL caused by L. braziliensis without success 87 . However, liposomal amphotericin showed a good response in two cases of co-infected MCL and HIV patients who had not responded to meglumine antimoniate 76,103 .…”

Coinfection of Leishmania guyanensis and Human Immunodeficiency Virus–Acquired Immune Deficiency Syndrome: Report of a Case of Disseminated Cutaneous Leishmaniasis in Ecuador

“…15 Furthermore, most of the patients infected in the Pacific coastal region of Ecuador will selfcure after a Leishmania infection, as demonstrated in a study where a high number of patients were cured without drug treatment. 16 It is well known that treatment response to antimonials in Leishmania-HIV coinfections tends to be poor (33-82%), 2,17 with a relapse rate of 14-57%, and a high mortality. 2 AMB, the second line of treatment as recommended by the MSP, was initiated in the patient, but he developed renal failure after the 14th dose.…”

Schwere orale Mukositis bei einem Patienten mit HIV-Infektion

“…Neuerkrankungen (davon gut 0,5 Mio viszerale Leishmaniosen). 90 % dieser Neuerkrankungen finden sich in den drei Hauptendemieregionen: indischer Subkontinent, Brasilien, Südsudan/Äthiopien[8,9,18]. Die WHO geht von ca.…”

“…Die WHO geht von ca. 70 000 Todesfällen pro Jahr durch Leishmaniose aus[8,18]. Nach dem Stich der Sandmücke mit Inokulation der Erreger in das Tab.…”