Co-exposure effects of urinary polycyclic aromatic hydrocarbons and metals on lung function: Mediating role of systematic inflammation
Lihong Wu,
Xue Lu,
Siying Zhang
et al.
Abstract:Background: Polycyclic aromatic hydrocarbons (PAHs) and metals were associated with decreased lung function, but co-exposure effects and underlying mechanism remained unknown.
Methods: Among 1,123 adults from National Health and Nutrition Examination Survey 2011-2012, 10 urinary PAHs, 11 urinary metals, and peripheral white blood cell (WBC) count were determined, and 5 lung function indices were measured. Least absolute shrinkage and selection operator, Bayesian kernel machine regression (BKMR), and quantile-b… Show more
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