Co-delivery of drug and DNA from cationic dual-responsive micelles derived from poly(DMAEMA-co-PPGMA)

Synthesis of cationic star polymers by simplified electrochemically mediated ATRP

“…Amphiphilic star copolymers composed of poly(2-dimethylaminoethyl methacrylate)-block-poly(n-butyl acrylate) (PDMAEMA-b-PBA) arms covalently linked to a β-CD core are especially interesting, because they can be used in biomedical applications, including drug delivery and tissue engineering. PDMAEMA is the most extensively studied pH-responsive polymer [45][46][47][48][49][50], because it is able to function as the pH-responsive component as it has a nitrogen moiety, which can be protonated by lowering the pH of the solution [48,49], and shows pH-dependent lower critical solution temperature behavior [45] and upper critical solution temperature behavior at low temperatures in the presence of multivalent counter ions [47]. Furthermore PBA is an industrially important polymer because of its low glass-transition temperature, durability, and potential use as a soft segment in thermoplastic elastomers [51,52].…”

Synthesis and characterization of monodispersed P(St-co-DMAEMA) nanoparticles as pH-sensitive drug delivery system

“…The NPs based on cationic pH-sensitive polymers with amino groups which exhibited remarkable swelling under acidic condition are widely reported [12][13][14]. N,N′-dimethylaminoethyl methacrylate (DMAEMA), a monomer with tertiary amine functional groups which could be protonated at acidic pH, has been used to prepare pH-sensitive NPs [15,16].…”

Smart poly(oligo(propylene glycol) methacrylate) hydrogel prepared by gamma radiation

“…When the temperature is raised above the LCST, the hydrophobicity of the POPGMA causes the polymer chains to collapse into each other, leading to the formation of particles. Thermoresponsive biocompatible copolymers based on OPGMA were recently prepared with OEGMA [30] and dimethylaminoethyl methacrylate (DMAEMA) [24,31] via ATRP. The LCST of the copolymers was varied by changing the ratios of the co-monomers.…”