Co-current crossflow microfiltration in a microchannel

Amar, Levy; Hill, Michael; Faria, Mónica; Guisado, Daniela; Rijn, C.J.M. van; Leonard, Edward F.

doi:10.1007/s10544-019-0362-4

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…During the microfiltration process, the fluid flows on top of the membrane surface to allow the permeation due to a pressure difference. Therefore, an efficient filter requires well-defined cross-sectional area, axial flow rate, and a specified fluid that can produce the required axial pressure gradient [272]. Studies have focused on simulating and regulating the trans-membrane pressure to enhance the filtration capabilities.…”

Section: Cross Flow Filtration Of Single Rbcs In Microchannelsmentioning

confidence: 99%

Advances in Microfluidics for Single Red Blood Cell Analysis

et al. 2023

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The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted great interests in recent years to filter, trap, analyze, and release single erythrocytes for various applications. Researchers in this field have highlighted the vast potential in developing micro devices for industrial and academia usages, including lab-on-a-chip and organ-on-a-chip systems. This article critically reviews the current state-of-the-art and recent advances of microfluidics for single RBC analyses, including integrated sensors and microfluidic platforms for microscopic/tomographic/spectroscopic single RBC analyses, trapping arrays (including bifurcating channels), dielectrophoretic and agglutination/aggregation studies, as well as clinical implications covering cancer, sepsis, prenatal, and Sickle Cell diseases. Microfluidics based RBC microarrays, sorting/counting and trapping techniques (including acoustic, dielectrophoretic, hydrodynamic, magnetic, and optical techniques) are also reviewed. Lastly, organs on chips, multi-organ chips, and drug discovery involving single RBC are described. The limitations and drawbacks of each technology are addressed and future prospects are discussed.

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Section: Cross Flow Filtration Of Single Rbcs In Microchannelsmentioning

confidence: 99%