Co-administration of Spondias mombin and Metformin mitigates Streptozotocin-induced hepatorenal injury

John, Ajibade Adeshina; Zabdiel, Abijo Ayodeji; Priscilla, Ajibade Testimony; David, Kehinde Busuyi; Adewale, Siyanbade Jacob; Aderemi, Adelakun Sunday; Atilola, Adeeyo Olusola

doi:10.1016/j.phyplu.2022.100360

Cited by 3 publications

(1 citation statement)

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“…24 Hypoglycaemic activity Induction of diabetes in experimental animals is commonly by chemical method with streptozotocin and alloxan. [56][57][58][59][60][61][62][63][64] It usually involve the destruction of the beta-cells of the Islets of Langerhans in the pancreas with a consequent reduction in synthesis and release of insulin. 56,63 Numerous studies have reported the hypoglycemic activities of S. mombin.…”

Section: Antioxidant Activitymentioning

confidence: 99%

Phytopharmacological Activities of Spondias mombinLinn: A Review

2024

TJPPS

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This review describes the phytopharmacological activities of Spondias mombin. Spondias mombin (S. mombin) is a fructiferous tree native to tropical areas like America, Brazil, Nigeria and West India. It belongs to the cashew family of Anacardiaceae. Spondias mombin has been used as an herbal medicine from ancient times. Spondias mombin plant parts (leaves, bark, seeds, and fruits) are used for therapeutic purposes. Traditionally, the plant is being used in inducing labour, preventing miscarriages, reducing inflammation, reducing blood glucose level, amongst others. Various plant parts are also used for non-medicinal purposes like the production of cider-like drinks, wine, soap and ornamental purposes. The main bioactive compounds reported in S. mombin include tannins, phenols, saponins, anthraquinones, berberine, naphthoquinones, sesquiterpenes, indole and quinoline alkaloids, proanthocyanins, and flavonoids. Spondias mombin possesses beneficial pharmacological properties that are well-utilized in medicinal herbal therapy of several disease conditions.

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