Cnidoscolus chayamansa hidropónica orgánica y su capacidad hipoglucemiante, calidad nutraceutica y toxicidad

Abstract


 
 
 La chaya es una planta con calidad nutricional y posee un alto potencial en la salud pública en el tratamiento de diabetes mellitus. La diabetes mellitus es una de las enfermedades crónico-degenerativas con mayor prevalencia en México. Por otra parte, en los últimos años se ha incrementando el interés por la evaluación de los efectos del consumo de extractos de plantas como alternativa inocua para el tratamiento de diabetes. Estudios recientes han demostrado que extractos de chaya (Cnidoscolus chayamansa) tienen propiedades antioxidantes. Sin embargo, se desconoce si las infusiones (extractos acuosos) de dicha planta poseen propiedades hipoglicemiantes. La capacidad hipoglicemiante y toxicidad de una infusión de hojas de chaya hidropónica producida orgánicamente fueron evaluadas mediante modelos in vivo, usando ratas macho Wistar albinas (evaluación de capacidad hipoglicemiante), y larvas de Artemia salina (determinación de toxicidad). Asimismo se determinaron el contenido fenólico y la capacidad antioxidante de la infusión. El consumo de la infusión evaluada redujo los niveles de glucosa de las ratas diabéticas, teniendo un mayor efecto hipoglicemiante que la aplicación de glibenclamida. La evaluación de toxicidad mostro que la infusión de hoja de chaya hidropónica orgánica no es toxica y es segura para su consumo como potencial agente hipoglicemiante.
 
 

Use of Chaya (Cnidoscolous chayamansa) Leaves for Nutritional Compounds Production for Human Consumption

“…It is well known that high temperatures increase the extraction rate of different compounds such as polyphenols. [9,49,50] On the other side, the highest concentration (71.3 mg GAE/g) found by Loarca-Piña et al [9] was obtained using an extensive extraction of 5 days at room temperature with hexane-acetone, and a second extraction with methanol was also applied.The differences observed in the total polyphenols could be due to different reasons such as the type of solvent used for extraction (acetone, ethanol, methanol, or water), total extraction time, harvesting conditions, crop age state [9,49], and the type of standard used for the calibration curve. The fact that similar amounts of polyphenols were present after protein extraction could indicate that protein-polyphenol conjugates were not formed during protein precipitation.…”

Genetic Diversity in Nutritious Leafy Green Vegetable—Chaya (Cnidoscolus aconitifolius)

“…Chaya decreases the level of blood glucose, which is most likely related to the level of glycosides found in the plant. In medical animal experiments, chaya consumption was shown to reduce blood glucose levels of diabetic rats (Valenzuela Soto et al 2015) and rabbits (Kuti and Torres 1996). Such studies, however, are not considered to be entirely conclusive.…”

“…Chaya is exceptionally high in calcium and iron (Berkelaar 2006). Calcium supports bone and dental health and is alleged to mitigate weight; iron supports the Table 6.6 Chemically identified pharmacologically functional groups and active substances of chaya and respective extraction methods (García-Rodríguez et al 2014;González-Laredo et al 2003;Kuti and Kuti 1999;Kuti and Torres 1996;Loarca-Piña et al 2010;Miranda Velásquez et al 2016;Molina-Cruz et al 1997;Obichi et al 2015;Santacruz et al 2013;Sarmiento-Franco et al 2003a, b;Valenzuela Soto et al 2015) Functional group Active substances Water Ethanol Methanol Hexane Flavonoid glycosides Amentoflavone, astragalin, catechin, dihydromyricetin, kaempferol, quercetin, rutin…”

Effects of the combination of Cnidoscolus aconitifolius and Metformin on the glycemia in streptozotocin-induced diabetes rats

“…For hundreds of years it has been used as food and as a remedy for various conditions, mainly against diabetes (Lorca-Piña et al, 2010). Valenzuela et al (2015) have reported the use of aqueous extracts of Cnidoscolus chayamansa cultivated by hydroponics in a model in Wistar rats with demonstrated hypoglycemic benefits comparable to glibencalmide effects. Ramos-Gomez et al (2017) also report finding a hypolipidemic and hypoglycemic effect.…”