CMR in Heart Failure

Sado, Daniel; Hasleton, Jonathan M; Herrey, Anna S; Moon, James

doi:10.4061/2011/739157

Cited by 8 publications

(5 citation statements)

References 65 publications

(63 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The disadvantages of CMR relate primarily to accessibility, cost and patient tolerance of procedure. Until more data are available to support the use of Z in routine clinical practice [31], CMR/ AT-derived Z will likely remain an imaging modality, which requires expertise from subspecialised imaging cardiologists, thereby limiting availability to the general population in contrast to echocardiography [29]. Further to this, it relies on the patient being able to lie flat for at least 40 min and to breath hold, which is not always feasible in an elderly population afflicted by cardiac disease [31].…”

Section: Cardiac Magnetic Resonance Methods To Assess Vascular Impedancementioning

confidence: 99%

Evaluation of contemporary methods to determine vascular impedance

Liulu

Hungerford

2023

Journal of Hypertension

View full text Add to dashboard Cite

The past decade has seen considerable growth in therapeutics and device technologies to treat patients with hypertension and other cardiovascular disease states. Uncoupling ventriculo-arterial interactions in these patients, however, is often complex and not adequately accounted for by arterial pressure or vascular resistance measurement alone. In reality, the global vascular load presented to the left ventricle (LV) includes both steady-state and pulsatile components. Whereas steady-state load is best represented by the vascular resistance, pulsatile load, which incorporates wave reflections and arterial stiffness, may oscillate during various phases of the cardiac cycle and is best determined by the vascular impedance (Z). In recent years, measurement of Z has become more readily accessible through an array of simultaneous applanation tonometry, echocardiography and cardiac magnetic resonance (CMR) techniques. In the following review, we evaluate existing and newer methods to assess Z so as to better understand the pulsatile characteristics of the human circulation in hypertension and other cardiovascular disease states.

show abstract

Section: Cardiac Magnetic Resonance Methods To Assess Vascular Impedancementioning

confidence: 99%

Evaluation of contemporary methods to determine vascular impedance

Liulu

Hungerford

2023

Journal of Hypertension

View full text Add to dashboard Cite

show abstract

“…Most CMR studies utilize LGE to evaluate for scar formation or cardiomyopathy; however, additional techniques can be used to provide real-time imaging during the respiratory cycle, myocardial blood flow stress, and edema imaging, among other uses. Gadolinium (an extracellular contrast agent) dramatically enhances the differences between relaxation times in normal and abnormal myocardium [18].…”

Section: Mechanism Of Mrimentioning

confidence: 99%

Cardiovascular Magnetic Resonance Imaging: A Prospective Modality in the Diagnosis and Prognostication of Heart Failure

Elmadi¹,

Kumar²,

Pugalenthi³

et al. 2022

Cureus

View full text Add to dashboard Cite

Heart failure (HF) is a clinical syndrome resulting from structural cardiac remodeling and altered function that impairs tissue perfusion. This article aimed to highlight the current diagnostic and prognostic value of cardiac magnetic resonance (CMR) in the management of HF and prospective future applications. Reviewed are the physics associated with CMR, its use in ischemic and non-ischemic causes of HF, and its role in quantifying left ventricular ejection fraction. It also emphasized that CMR allows for noninvasive morphologic and functional assessment, tissue characterization, blood flow, and perfusion evaluation in patients with suspected or diagnosed HF. CMR has become a crucial instrument for the diagnosis, prognosis, and therapy planning in patients with HF and cardiomyopathy due to its accuracy in quantifying cardiac volumes and ejection fraction (considered the gold standard) as well as native and post-contrast myocardial tissue characterization.

show abstract

“…Cardiovascular magnetic resonance imaging (CMR) is increasingly used in the diagnostic workflow of patients with suspected or proven HF, including detecting scars and ischaemia, revealing subendocardial defects through stress perfusion and quantifying infiltration or fibrosis during gadolinium analysis [5]. Several methods have been developed to assess diastolic function and, by extension, PCWP [6].…”

Section: Introductionmentioning

confidence: 99%

The Left Atrial Area Derived Cardiovascular Magnetic Resonance Left Ventricular Filling Pressure Equation Shows Superiority over Integrated Echocardiography

Grafton-Clarke,

Matthews,

Gosling

et al. 2023

Medicina

View full text Add to dashboard Cite

Background and objectives: Evaluating left ventricular filling pressure (LVFP) plays a crucial role in diagnosing and managing heart failure (HF). While traditional assessment methods involve multi-parametric transthoracic echocardiography (TTE) or right heart catheterisation (RHC), cardiovascular magnetic resonance (CMR) has emerged as a valuable diagnostic tool in HF. This study aimed to assess a simple CMR-derived model to estimate pulmonary capillary wedge pressure (PCWP) in a cohort of patients with suspected or proven heart failure and to investigate its performance in risk-stratifying patients. Materials and methods: A total of 835 patients with breathlessness were evaluated using RHC and CMR and split into derivation (85%) and validation cohorts (15%). Uni-variate and multi-variate linear regression analyses were used to derive a model for PCWP estimation using CMR. The model’s performance was evaluated by comparing CMR-derived PCWP with PCWP obtained from RHC. Results: A CMR-derived PCWP incorporating left ventricular mass and the left atrial area (LAA) demonstrated good diagnostic accuracy. The model correctly reclassified 66% of participants whose TTE was ‘indeterminate’ or ‘incorrect’ in identifying raised filling pressures. On survival analysis, the CMR-derived PCWP model was predictive for mortality (HR 1.15, 95% CI 1.04–1.28, p = 0.005), which was not the case for PCWP obtained using RHC or TTE. Conclusions: The simplified CMR-derived PCWP model provides an accurate and practical tool for estimating PCWP in patients with suspected or proven heart failure. Its predictive value for mortality suggests the ability to play a valuable adjunctive role in echocardiography, especially in cases with unclear echocardiographic assessment.

show abstract

CMR in Heart Failure

Cited by 8 publications

References 65 publications

Evaluation of contemporary methods to determine vascular impedance

Evaluation of contemporary methods to determine vascular impedance

Cardiovascular Magnetic Resonance Imaging: A Prospective Modality in the Diagnosis and Prognostication of Heart Failure

The Left Atrial Area Derived Cardiovascular Magnetic Resonance Left Ventricular Filling Pressure Equation Shows Superiority over Integrated Echocardiography

Contact Info

Product

Resources

About