“…Recently, building upon technologies developed for particle physics (Turala, 2005; Wermes, 2005; Turchetta et al, 2007; Delpierre, 2014), pixelated detectors developed for X-ray imaging have been adopted for electron imaging (Clough et al, 2014; McMullan et al, 2014; McGrouther et al, 2015; Tate et al, 2016; Mir et al, 2017; Tinti et al, 2018). Compared with charge coupled device (CCD)-based detectors, these direct electron detectors (DEDs) typically offer much lower noise levels, improved detector quantum efficiency (DQE), and modulation transfer function (MTF), some degree of radiation hardness, and crucially, fast readout of the images.…”