Cmai: Predicting Antigen-Antibody Interactions from Massive Sequencing Data
Bing Song,
Kaiwen Wang,
Saiyang Na
et al.
Abstract:The interaction between antigens and antibodies (B cell receptors, BCRs) is the key step underlying the function of the humoral immune system in various biological contexts. The capability to profile the landscape of antigen-binding affinity of a vast number of BCRs will provide a powerful tool to reveal novel insights at unprecedented levels and will yield powerful tools for translational development. However, current experimental approaches for profiling antibody-antigen interactions are costly and time-cons… Show more
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