Clusters of Shingles

Gilks, Charles F.; Juel-Jensen, Bent; Martinez‐Martín, Pablo; Estévez, E; Rapún, José L.; Echevarría, J M; García-Sáiz, Alfredo

doi:10.1016/s0140-6736(85)92606-6

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…In some outbreaks the descriptive epidemiology suggests hypotheses for which there are no biological explanations (eg a cluster of three cases of aplastic anaemia in children 3 ) or which go against the accepted microbiological theory (eg an outbreak of shingles [4][5][6] ). In the practice of infectious disease control, the framework of proven microbiological causes and modes of transmission enables statistical data to be interpreted confidently.…”

Section: Developing a Hypothesismentioning

confidence: 99%

Nordic Workshop addressing case-control studies and food borne infections

2004

TemaNord

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Section: Developing a Hypothesismentioning

confidence: 99%

Nordic Workshop addressing case-control studies and food borne infections

2004

TemaNord

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The epidemiology of Herpes Zoster

Cooper

1987

Eye

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SummaryThe epidemiology of Zoster is analysed by means of data acquired from the Zoster Clinic at Moorfields and the RCGP Research Unit. It complements and extends previous surveys, using much larger and consistent data, showing the effects of age, sex and season. The behaviour in the population as a whole and the pathogenesis are discussed; a model is proposed to explain the characteristics of some of the data, particularly the effects of age and non-specific stresses. Material and MethodsThe Zoster Clinic has been functioning for the last 15 years and during this time consistent records have been kept for nearly all attendances. These were recently put into computer storage, which has made overall statistical assessment and recall much easier. To date, about 1,200 patient records have been entered.The Weekly Returns Service of the RCGP pro vides data from 1967 and now covers a population of over 200,000 in 39 general practices scattered around England (33), Wales (4), Scotland (1) and N. Ireland (1). The figures for the last 3 years are accessible from computer, giving weekly numbers broken down by sex and 5 age groups. HZ and chickenpox are fortunately included in these returns.The data were prepared in graphical form for the sake of clarity, and no statistical tests were performed.

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Aseptic Meningitis Due to Varicella-Zoster Virus: Serum Antibody Levels and Local Synthesis of Specific IgG, IgM, and IgA

Echevarría¹,

Martinez‐Martín²,

Tellez³

et al. 1987

Journal of Infectious Diseases

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We used an indirect enzyme immunoassay to describe the evolution of serum levels and the intrathecal production of IgG, IgA, and IgM antibodies to varicella-zoster virus (VZV) in eight patients with a syndrome of acute aseptic meningitis (AAM) and evidence of intrathecal production of VZV-specific IgG antibodies. Four of the eight patients showed no cutaneous zoster while hospitalized. Our results suggested an etiologic relation between VZV and AAM in all cases. Furthermore, we observed some differences in the pattern of evolution of antibodies in serum and cerebrospinal fluid in relation to the presence or absence of cutaneous lesions in our patients. These differences could reflect different pathogenic mechanisms in the spread of VZV to the central nervous system and in the production of the AAM syndrome.

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Clusters of Shingles

Cited by 3 publications

References 2 publications

Nordic Workshop addressing case-control studies and food borne infections

Nordic Workshop addressing case-control studies and food borne infections

The epidemiology of Herpes Zoster

Aseptic Meningitis Due to Varicella-Zoster Virus: Serum Antibody Levels and Local Synthesis of Specific IgG, IgM, and IgA

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