Clusters of nonhistone chromosomal protein HMG1 molecules in intact chromatin

Recent observations and hypotheses on the structure of chromatin are reviewed. Elementary "subunit" for higher structural orders is the nucleosome, consisting of a histone octamer and doublehelical DNA wrapped around it. During the last years details of the nucleosomal structure could be deduced down to a resolution of 2 nm. In the chromatin fiber, built up by (mono-)nucleosomes, the superhelical DNA has a tertiary structure, from which structures of still higher order (quaternary structure of DNA) can be formed. The correlation of these structures to the terms euchromatin and heterochromatin are discussed. Finally, some functional aspects, especially transcription and replication, are discussed in view of the new knowledge of chromatin structure.

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Struktureller Aufbau des Chromatins

Harbers

Brust

Notbohm

1982

Klin Wochenschr

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Influence of high-mobility-group nonhistone chromosomal proteins 1 and 2 on the digestion of chromatin with micrococcal nuclease

Marekov

Beltchev

1982

Archives of Biochemistry and Biophysics

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A study on the amount of high-mobility-group chromatin proteins in T-cells at different stages of differentiation

Russanova

Andó

1985

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expres

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Clusters of nonhistone chromosomal protein HMG1 molecules in intact chromatin

Cited by 9 publications

References 12 publications

Struktureller Aufbau des Chromatins

Struktureller Aufbau des Chromatins

Influence of high-mobility-group nonhistone chromosomal proteins 1 and 2 on the digestion of chromatin with micrococcal nuclease

A study on the amount of high-mobility-group chromatin proteins in T-cells at different stages of differentiation

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