Clustering of RNA co-expression network identifies novel long non-coding RNA biomarkers in squamous cell carcinoma
Liisa Nissinen,
Josefiina Haalisto,
Pilvi Riihilä
et al.
Abstract:Long non-coding RNAs (lncRNAs) have emerged as important players in cancer progression. Cutaneous squamous cell carcinoma (cSCC) is the most common metastatic skin cancer with increasing incidence worldwide. The prognosis of the metastatic cSCC is poor, and currently there are no established biomarkers to predict metastasis risk or specific therapeutic targets for advanced or metastatic cSCC. To elucidate the role of lncRNAs in cSCC, RNA sequencing of patient derived cSCC cell lines and normal human epidermal … Show more
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