Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas13a: Future Hope to Tackle Anti-Microbial Resistance

Suvvari, Tarun Kumar; Kandula, Venkata Dinesh Kumar; Kandi, Venkataramana; Thomas, Vimal

doi:10.1177/11786361231178623

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…Other work carried out on the topic of gene regulation and silencing is also mentioned, using specific target RNA sequences in E. coli and Leptotrichia Shahii. It is concluded that this system has enormous potential and still needs to be perfected for use in research, diagnosis, and therapy [92].…”

Section: ε-Viniferinmentioning

confidence: 99%

Polyphenols and CRISPR as Quorum Quenching Agents in Antibiotic-Resistant Foodborne Human Pathogens (Salmonella Typhimurium, Campylobacter jejuni and Escherichia coli 0157:H7)

Higuera-Ciapara,

Benitez-Vindiola,

Figueroa-Yañez

et al. 2024

Foods

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Antibiotic resistance in foodborne pathogens is an increasing threat to global human health. Among the most prevalent antibiotic-resistant bacteria are Salmonella enterica serovar Typhimurium, Campylobacter jejuni and E. coli 0157:H7. Control of these and other pathogens requires innovative approaches, i.e., discovering new molecules that will inactivate them, or render them less virulent without inducing resistance. Recently, several polyphenol molecules have been shown to possess such characteristics. Also, the use of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) approaches has recently been proposed for such purpose. This review summarizes the main findings regarding the application of both approaches to control the above-mentioned foodborne pathogens by relying on Quorum Sensing interference (Quorum Quenching) mechanisms and highlights the avenues needed for further research.

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Section: ε-Viniferinmentioning

confidence: 99%

Polyphenols and CRISPR as Quorum Quenching Agents in Antibiotic-Resistant Foodborne Human Pathogens (Salmonella Typhimurium, Campylobacter jejuni and Escherichia coli 0157:H7)

Higuera-Ciapara,

Benitez-Vindiola,

Figueroa-Yañez

et al. 2024

Foods

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show abstract

“…Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology can be used to overcome the multidrug resistances. 6 …”

mentioning

confidence: 99%

Candida Auris: An Emerging Multidrug-Resistant Fungal Pathogen in the United States and the Urgent Call for Action

Kumar,

Mukherjee,

Banerjee

et al. 2023

Microbiol�Insights

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Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas13a: Future Hope to Tackle Anti-Microbial Resistance

Cited by 2 publications

References 5 publications

Polyphenols and CRISPR as Quorum Quenching Agents in Antibiotic-Resistant Foodborne Human Pathogens (Salmonella Typhimurium, Campylobacter jejuni and Escherichia coli 0157:H7)

Polyphenols and CRISPR as Quorum Quenching Agents in Antibiotic-Resistant Foodborne Human Pathogens (Salmonella Typhimurium, Campylobacter jejuni and Escherichia coli 0157:H7)

Candida Auris: An Emerging Multidrug-Resistant Fungal Pathogen in the United States and the Urgent Call for Action

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