“…Additionally, our quantitative evaluation method employing the holes to simulate small mass changes could be applied to evaluate not only MCs, but also bone defects or caries in clinical situations. Weerawanich et al 17 developed a new image quality evaluation method that had a higher correlation with observer performance with several cut-off values; however, its relationship to diagnostic performance is still unclear. Although the number of cut-off values (threshold gray value or ΔG) in this method is limited, we confirmed that diagnostic performance was reflected in the number of extracted holes.…”