Cluster of flowers – The unseen of syphilis

Ashwini, P; George, Anu; Betkerur, Jayadev

doi:10.4103/idoj.idoj_89_19

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…The presentation of secondary syphilis as a single lesion, or even as localized lesions, is very rare. The localized pattern of secondary syphilis is referred to as the corymbose arrangement, consisting of a greater papule surrounded by smaller satellite lesions [77,78]. However, despite being localized, the lesions of corymbose pattern are multiple.…”

Section: Discussionmentioning

confidence: 99%

Syphilis, the Great Imitator—Clinical and Dermoscopic Features of a Rare Presentation of Secondary Syphilis

Cantisani

Rega

Ambrosio

et al. 2023

IJERPH

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Syphilis is characterized by a wide range of variable clinical symptoms; therefore, it is often referred to as “The Great Imitator”. Here, we report the case of a 69-year-old hepatitis-C-positive MSM patient, who was admitted to our clinic due to a solitary firm painless erythematous maculopapular lesion with a central crater-like crust on the upper right thigh that occurred two months prior. The dermoscopy showed an erythematous, copper-colored, oval lesion with diffuse monomorphic dotted and glomerular vessels, central crust, and circular scaling (Biett’s sign). The histological findings ruled out neoplasia and described a plasma cell infiltrate and endothelial swelling. Finally, the combination of the dermoscopic image, histological findings and the additionally acquired knowledge about the sexual history of the patient at the second visit led to the diagnosis, which was then confirmed with serological tests. Dermoscopy may become a supportive tool to facilitate the recognition of secondary syphilis; however, the reporting of these atypical cases is crucial to highlight the many faces of the disease so that clinicians consider syphilis as part of the differential diagnosis of non-specific lesions.

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Section: Discussionmentioning

confidence: 99%

Syphilis, the Great Imitator—Clinical and Dermoscopic Features of a Rare Presentation of Secondary Syphilis

Cantisani

Rega

Ambrosio

et al. 2023

IJERPH

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Corymbiform syphilis: A rare dermatological presentation

Al-Ali,

Almarzooqi,

Padovese

2024

Int J STD AIDS

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Syphilis is often referred to as the ‘great imitator’ due to its diverse clinical manifestations throughout its clinical stages and polymorphic nature. We report a case of a 24-year-old man-who-has-sex-with-men presenting with an atypical syphilitic rash on the trunk, with a corymbiform appearance. This case highlights the necessity for clinicians to maintain a high index of suspicion for sexually transmitted infections, especially when there are skin manifestations of an uncertain nature.

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Cluster of flowers – The unseen of syphilis

Cited by 2 publications

References 3 publications

Syphilis, the Great Imitator—Clinical and Dermoscopic Features of a Rare Presentation of Secondary Syphilis

Syphilis, the Great Imitator—Clinical and Dermoscopic Features of a Rare Presentation of Secondary Syphilis

Corymbiform syphilis: A rare dermatological presentation

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