Cluster efficient pangenome graph construction with nf-core/pangenome
Simon Heumos,
Michael F. Heuer,
Friederike Hanssen
et al.
Abstract:Motivation: Pangenome graphs offer a comprehensive way of capturing genomic variability across multiple genomes. However, current construction methods often introduce biases, excluding complex sequences or relying on references. The PanGenome Graph Builder (PGGB) addresses these issues. To date, though, there is no state-of-the-art pipeline allowing for easy deployment, efficient and dynamic use of available resources, and scalable usage at the same time. Results: To overcome these limitations, we present nf-c… Show more
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