Cluster Analysis of Cancer Incidence among Smoking Men in China

Abstract

In recent years, the incidence rate and mortality of lung cancer have shown a rapid growth trend, and its pathogenic factors have also attracted widespread attention. At present, it is universally acknowledged that smoking has a strong correlation with lung cancer. Statistics show that 80% of lung cancer patients have smoking history. At the same time, it is also pointed out that quitting smoking in normal people can change the composition of intestinal flora; And in the normal population and patients with inflammatory bowel disease, the composition of intestinal flora between smokers and non-smokers is different. But now, in colorectal adenoma and colorectal cancer patients, the impact of smoking on intestinal flora is still unclear. To sum up, this topic plans to further study the relationship between smoking, intestinal flora and colorectal tumors. Cluster analysis was used to comprehensively evaluate and classify the incidence data of malignant tumors in 32 tumor registries in China, so as to further understand the regional distribution characteristics of malignant tumors in China. The results showed that compared with normal healthy people, the composition of intestinal flora in patients with colorectal cancer was different, and smoking could also change the intestinal flora. However, whether intestinal flora plays a role in promoting the occurrence and development of colorectal cancer by smoking needs further study.