Cluster Analysis as a Method for Determining Size Ranges for Spinal Implants: Disc Lumbar Replacement Prosthesis Dimensions from Magnetic Resonance Images

Dang, Lei; Holder, Roger; Smith, Francis W.; Wardlaw, Douglas; Hukins, D. W. L.

doi:10.1097/01.brs.0000248414.62802.42

Cited by 5 publications

(2 citation statements)

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“…Discriminant analysis is a multivariate statistical method that can distinguish newly acquired samples according to the quantitative characteristics of an existing set of observed samples. 12 In the present paper, we utilized discriminant analysis to determine how well the clustering analysis was able to classify the TMJs based on shape. One important metric for evaluating such classification results is the proportion correct.…”

Section: Methodsmentioning

confidence: 99%

Three-Dimensional Measurement and Cluster Analysis for Determining the Size Ranges of Chinese Temporomandibular Joint Replacement Prosthesis

Zhang

Meng

et al. 2016

Medicine

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The aim of this study was to investigate the osseous characteristics of Chinese temporomandibular joint (TMJ) and detect the size clusters for total joint prostheses design.Computer tomography (CT) data from 448 Chinese adults (226 male and 222 female, aged from 20 to 83 years, mean age 39.3 years) with 896 normal TMJs were chosen from the Department of Radiology in the Shanghai 9th People's Hospital. Proplan CMF 1.4 software was used to reconstruct the skulls. Three-dimensional (3D) measurements of the TMJ fossa and condyle-ramus units with 13 parameters were performed. Size clusters for prostheses design were determined by hierarchical cluster analyses, nonhierarchical (K-means) cluster analysis, and discriminant analysis.The glenoid fossa was grouped into 3 clusters, and the condyle-ramus units were grouped into 4 clusters. Discriminant analyses were capable of correctly classifying 97.24% of the glenoid fossa and 94.98% of the condyle-ramus units. The means and standard deviations for the parameter values in each cluster were determined.Fossa depth and angles between the condyle and ramus were important parameters for Chinese TMJ prostheses design. 3D measurements and cluster analysis of the osseous morphology of the TMJ provided an anatomical reference and identified the dimensions of the minimum numbers of prosthesis sizes required for Chinese TMJ replacement.

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Section: Methodsmentioning

confidence: 99%

Three-Dimensional Measurement and Cluster Analysis for Determining the Size Ranges of Chinese Temporomandibular Joint Replacement Prosthesis

Zhang

Meng

et al. 2016

Medicine

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“…With respect to the biomechanical specifications, based on our study, the implant should meet the following requirements: Adapts the equations of the movement of the intact ICR of the joint to the post-surgical ICR [3 , 88] Behaves as a shock absorbing mechanism [58] Allows the load absorption within the implant so that adjacent levels do not overload [11] Biocompatible [37] Low implant wear [104] Different sizes to adapt to different patient geometries [59] Non-complex geometry in order to be readily manufactured [90] …”

Section: Discussionmentioning

confidence: 99%

ICR in human cadaveric specimens: An essential parameter to consider in a new lumbar disc prosthesis design

Vanaclocha¹,

Atienza

Vanaclocha

et al. 2020

North American Spine Society Journal (NASSJ)

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Study design: Biomechanical study in cadaveric specimens. Background:The commercially available lumbar disc prostheses do not reproduce the intact disc's Instantaneous centre of Rotation (ICR), thus inducing an overload on adjacent anatomical structures, promoting secondary degeneration.Aim: To examine biomechanical testing of cadaveric lumbar spine specimens in order to evaluate and define the ICR of intact lumbar discs.Material and Methods: Twelve cold preserved fresh human cadaveric lumbosacral spine specimens were subjected to computerized tomography (CT), magnetic resonance imaging (MRI) and biomechanical testing. Kinematic studies were performed to analyse range of movements in order to determine ICR.Results: Flexoextension and lateral bending tests showed a positive linear correlation between the angle rotated and the displacement of the ICR in different axes.Discussion: ICR has not been taken into account in any of the available literature regarding lumbar disc prosthesis. Considering our results, neither the actual ball-and-socket nor the withdrawn elastomeric nucleus models fit the biomechanics of the lumbar spine, which could at least in part explain the failure rates of the implants in terms of postoperative failed back syndrome (low back pain). It is reasonable to consider then that an implant should also adapt the equations of the movement of the intact ICR of the joint to the post-surgical ICR.Conclusions: This is the first cadaveric study on the ICR of the human lumbar spine. We have shown that it is feasible to calculate and consider this parameter in order to design future prosthesis with improved clinical and biomechanical characteristics. * Corresponding author.spine [78] . When the intervertebral disc degenerates, it loses its capacity to transmit this load and thus may become a source of low back pain [66] .Lumbar disc arthroplasty was introduced in 1960 [27] , although results were not promising until the 1980 ′ s [7 , 36 , 60 , 115] . The aim of this surgical procedure is to preserve motion as well as to avoid spinal fusion related complications and side-effects. The first successfully implanted device was the SB Charitè [7 , 15] . The initial suboptimal results, which occurred due to mechanical failure [7 , 19 , 52 , 101 , 102] , were mitigated by repeatedly improving on the design [60] . Ever since, many other disc

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11 Cluster Analysis

Shannon¹

2007

Handbook of Statistics

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Cluster Analysis as a Method for Determining Size Ranges for Spinal Implants: Disc Lumbar Replacement Prosthesis Dimensions from Magnetic Resonance Images

Abstract: Cluster analysis has been successfully used to find the dimensions of the minimum number of prosthesis sizes required to replace L3-L4 to L5-S1 discs; the range of sizes would enable them to be used at higher lumbar levels in some patients.

Cited by 5 publications

References 23 publications

Three-Dimensional Measurement and Cluster Analysis for Determining the Size Ranges of Chinese Temporomandibular Joint Replacement Prosthesis

Three-Dimensional Measurement and Cluster Analysis for Determining the Size Ranges of Chinese Temporomandibular Joint Replacement Prosthesis

ICR in human cadaveric specimens: An essential parameter to consider in a new lumbar disc prosthesis design

11 Cluster Analysis

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