Clubfoot: Etiology and treatment

Anand, Ashish; Sala, Debra A.

doi:10.4103/0019-5413.38576

Cited by 49 publications

(56 citation statements)

References 42 publications

(51 reference statements)

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“…Structural clubfoot is distinguished from positional clubfoot in that the foot cannot be moved into a normal position; additionally, positional clubfoot is believed to result from uterine constraint. 11,12 The prevalence of structural clubfoot is approximately 1 per 1,000 births. 13,14 …”

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confidence: 99%

Use of Selective Serotonin-Reuptake Inhibitors During Pregnancy and the Risk of Clubfoot

et al. 2014

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Background Selective serotonin-reuptake inhibitors (SSRIs) are the most commonly prescribed anti depressants. Previous studies have suggested that SSRIs may increase the risk of birth defects, including clubfoot. Using data from a population-based case-control study, we evaluated whether SSRI use increased the risk of clubfoot. Methods Mothers were interviewed within one year after delivery about sociodemographic factors, pregnancy events and exposures. They were specifically asked if they experienced depression or anxiety or if they took any of the following SSRIs: citalopram, escitalopram, fluvoxamine, paroxetine, sertraline or fluoxetine. We used logistic regression models to calculate odds ratios (ORs) and 95% confidence intervals. Results We included a total of 622 clubfoot cases and 2002 non-malformed controls born between 2006 and 2011 in Massachusetts, New York, and North Carolina. For the second or third lunar month of pregnancy (the relevant gestational period), SSRI use for a period of more than 30 days was higher in case mothers (5%) than control mothers (3%). After adjustment for maternal smoking and body mass index, the OR for any SSRI use and clubfoot was 1.8 (95% confidence interval=1.1–2.8). When individual SSRIs were examined, ORs were elevated for sertraline (1.6 [0.8–3.2]), paroxetine (9.2 [0.7–484.6]) and escitalopram (2.9 [1.1–7.2]). Conclusion Our data suggest an increased risk of clubfoot occurrence in relation to SSRI use. Drug-specific risks varied widely and some estimates were unstable.

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confidence: 99%

Use of Selective Serotonin-Reuptake Inhibitors During Pregnancy and the Risk of Clubfoot

et al. 2014

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“…Congenital clubfoot, irrespective of treatment by conservative or operative means, has a tendency to relapse [1][2][3]. The relapsed foot following a nonoperative intervention is relatively easier to manage than the one following open surgical release.…”

Section: Introductionmentioning

confidence: 98%

Ilizarov in relapsed clubfoot

Gupta

Bither²

2013

Journal of Pediatric Orthopaedics B

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This study aims to retrospectively evaluate the results of soft tissue distraction using Ilizarov in relapsed clubfeet following a previous posteromedial soft tissue release. This study, as compared with previous studies, has a cohort of patients with relapsed clubfeet only following posteromedial soft tissue release. Fifteen patients (16 feet) were assessed using the International Clubfoot Study Group score and plantigrade foot was achieved in all except one patient who had equinus deformity. Fourteen feet were graded as showing excellent or good result on the basis of the International Clubfoot Study Group (ICFSG) score. Although no patient had an ICFSG score of 0, parental satisfaction was good. This report supports the use of Ilizarov as the benefits offered outweigh the risk of associated complications, making this potentially cumbersome apparatus a useful tool in the armamentarium to treat relapsed clubfeet following soft tissue release.

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“…It is generally agreed now that the initial treatment should be conservative and should start in first week after birth. 2 While most of the mild and moderately deformed feet get clinically corrected, these should be assessed radiologically, to see if true correction is achieved. The remaining feet which resist conservative treatment, usually require surgical correction.…”

Section: Introductionmentioning

confidence: 99%

An evaluation of congenital talipes equinovarus patients treated by various methods

2020

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Background: Idiopathic congenital talipes equinovarus is one of the commonest congenital anomaly. Although treatment provides many options, near universal agreement exists that initial management should consist of gentle manipulation of the affected foot. In developing country like India presentation is extremely variable from soon after birth to very late childhood and irregular follow up makes treatment more difficult.Methods: 100 cases of congenital talipes equinovarus who attended the Orthopedics OPD of our hospital (March 2013 to 2016) were taken up. In neonates with delicate skin, the passive manipulation was demonstrated to the mother which they did 5-6 times daily. The application of plaster of Paris cast and passive manipulation was done every 15th day upto 3 months of age. After the 3-month age, passive manipulation was done every 3 weeks. If no normalization, surgery was advised and done to correct the resistant component accordingly. All the analyses were performed in R-programming language (R- 3.0.0).Results: 6 cases,10 feet were lost during follow-up. Results were assessed in 134 feet, 128 cases managed conservatively, 13 surgically. Results were assessed according to clinical, radiological criteria of Beatson and Pearson. 13 feet were operated of 144 feet,11 cases posteromedial soft tissue release (PMSTR) was done. In two Joshi’s external stabilizing system (JESS) fixator was applied.Conclusions: Majority of cases can be treated successfully by conservative means and only in 11 cases PMSTR was done, 2 cases of relapsed feet JESS was applied.

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Clubfoot: Etiology and treatment

Cited by 49 publications

References 42 publications

Use of Selective Serotonin-Reuptake Inhibitors During Pregnancy and the Risk of Clubfoot

Use of Selective Serotonin-Reuptake Inhibitors During Pregnancy and the Risk of Clubfoot

Ilizarov in relapsed clubfoot

An evaluation of congenital talipes equinovarus patients treated by various methods

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