CLSY docking to Pol IV requires a conserved domain critical for small RNA biogenesis and transposon silencing
Luisa Felgines,
Bart Rymen,
Laura M. Martins
et al.
Abstract:Eukaryotes must balance the need for gene transcription by RNA polymerase II (Pol II) against the danger of mutations caused by transposable element (TE) proliferation. In plants, these gene expression and TE silencing activities are divided between different RNA polymerases. Specifically, RNA polymerase IV (Pol IV), which evolved from Pol II, transcribes TEs to generate small interfering RNAs (siRNAs) that guide DNA methylation and block TE transcription by Pol II. While the Pol IV complex is recruited to TEs… Show more
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