Clozapine-Induced Tardive Dystonia (Blepharospasm)

Duggal, D.P.M. Harpreet S.; Mendhekar, D.P.M. D.N.

doi:10.1176/jnp.2007.19.1.86

Cited by 23 publications

(7 citation statements)

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“…In such cases switching to clozapine may reveal suppressed TD (Bruscas et al, 2007;Duggal and Mendhekar, 2007;Ertugrul and Demir, 2005;Li et al, 2009;Raguraman and Vijaysagar, 2007). In the few case reports suggesting that clozapine induces TD most of the patients had a history of long-term use of FGAs.…”

Section: B Switching To Clozapinementioning

confidence: 99%

Tardive Dyskinesia: Clinical Presentation and Treatment

Harten

Tenback

2011

International Review of Neurobiology

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Section: B Switching To Clozapinementioning

confidence: 99%

Tardive Dyskinesia: Clinical Presentation and Treatment

Harten

Tenback

2011

International Review of Neurobiology

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“…Until recently, it was suggested that only antipsychotic agents cause TS; however, today it is known that medications from a variety of chemical groups and classes with sundry therapeutic purposes may also induce these disturbances, including clozapine . These agents include antidepressants, calcium channel blockers, antiemetic, antiepileptic, anti‐parkinsonian, anticholinergic medications, mood stabilizers and many others .…”

mentioning

confidence: 99%

Tardive dyskinesia (syndrome): Current concept and modern approaches to its management

Lerner

Miodownik

Lerner

2015

Psychiatry Clin Neurosci

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Tardive dyskinesia is a serious, disabling and potentially permanent, neurological hyperkinetic movement disorder that occurs after months or years of taking psychotropic drugs. The pathophysiology of tardive dyskinesia is complex, multifactorial and still not fully understood. A number of drugs were tried for the management of this motor disturbance, yet until now no effective and standard treatment has been found. It is very disappointing to realize that the introduction of antipsychotics from the second generation has not significantly decreased the prevalence and incidence of tardive dyskinesia. Therefore, the management of this motor disturbance remains an actual topic as well as a challenge for clinicians. This review summarizes recent relevant publications concerning the treatment of tardive dyskinesia.

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“…8 This surgery could alter drug oral bioavailability significantly according to each drugspecific properties, such as absorption site and drug formulation, possibly leading to relapse of the psychopathology postsurgery. [9][10][11] However, to our knowledge, the impact of BPD/DS on psychotropic drugs pharmacokinetics has never been studied. Thus, clinicians lack guidance on which antidepressant agent or formulation to use and whether target dosing ranges significantly changes after BPD/DS.…”

Section: Treating Depression Following Biliopancreatic Diversion With...mentioning

confidence: 99%