Cloud Point Extraction of Carbendazim Pesticide in Foods and Environmental Matrices Prior to Visible Spectrophotometric Determination

Abstract

Two simple eco-friendly methods are described for nano-determination of carbendazim (MBC) pesticide in real samples. These methods are based on oxidation of MBC pesticide with Fe (III) ions in acidic medium. The formed Fe(II) ions reacts with potassium ferricyanide to form blue colored product (method A) which can easily be extracted into nonionic surfactant solution of Triton X-114 at cloud point temperature (CPT) of 55°C and MBC determined spectrophotometrically at absorption maximum of 685 nm with apparent molar absorptivity of 2.07x10 4 L mol-1 cm-1. The Method B is based on the reaction of the formed Fe (II) with 2, 2'-bipyridyl to form a stable orange colored complex which can also be extracted by Triton X-114 at the same CPT and MBC determined spectrophotometrically at absorption maximum of 521 nm with apparent molar absorptivity of 1.83x10 4 L mol-1 cm-1. Optimization of the experimental parameters was described and interferences study also examined. Under the optimum conditions established, the calibration graphs for MBC were linear in the range of 0.5-13 and 1-20 ng mL-1 , giving the detection limits of 0.46 and 0.49 ng mL-1 with enrichment factors of 85.7 and 38.9 fold for method A and B respectively. The average percent recoveries in the real spiked samples were (97.86±1.06%) and (98.66±0.93%), giving a precision in terms of %RSD in the range of 1.25-2.97% and 0.37-1.42% for method A and B respectively. The proposed methods were applied to the determination of MBC in vegetables, orange, and water samples.

Determination of carcinogenic herbicides in milk samples using green non-ionic silicone surfactant of cloud point extraction and spectrophotometry

“…In the European Union (EU), content residues in milk and cream are not higher than 50 µg l −1 [2]. Because of these restrictions, analytical methods are required for monitoring the widespread distribution and it is highly desirable that these be environmentally friendly 'green' analytical methods [3].…”

Visible Spectrophotometric Determination of Metochlopramide Hydrochloride at Trace Levels in Various Samples after Cloud Point Extraction Using Derivatization Reaction

“…The efforts in this trend are continuing to design new CPE procedures according to the successful attempts that are made for the first time in our research groups in exploiting the cloud point extraction (CPE) and the adoption of derivatization reactions in converting organic compounds (drugs and pesticides) to the colored derivatives that capable to be extracted by using surfactant as an extracting medium [24][25][26][27] . In the present work, drug metoclopramide hydrochloride ( Figure 1) is selected as a model for designing new CPE procedures after using two coupling agents for its extraction and determination by visible spectrophotometry.…”