Fragility functions have been developed to evaluate the damageability of fully grouted and partially grouted reinforced masonry shear walls subjected to inplane seismic loading. Six damage states are considered, representing different levels of flexure, diagonal shear, and sliding shear damage. For each damage state, two classes of fragility functions have been developed. One has the story-drift ratio as the demand parameter. The other uses normalized demand parameters that account for the specific loading condition and design details of a wall component. All the fragility functions are derived from experimental data except for those developed for partially grouted walls and the sliding shear damage state. With both classes of fragility functions, the seismic damageability of flexure-dominated cantilever reinforced masonry shear walls in a four-story building has been assessed. It has been shown that the normalized flexural demand parameter provides a better correlation to the degree of damage developed in a wall than the story-drift ratio.