Closure of Oroantral Communication With Plasma-Rich Fibrin Membrane

Abstract

Oroantral communication (OAC) is the opening between the maxillary sinus and oral cavity. It may cause oroantral fistula or maxillary sinusitis if left untreated. The surgical closure of the OAC within 48 hours was recommended to avoid the complications like sinus infections. The aim of this study is to evaluate the treatment of OACs with plasma-rich fibrin (PRF) which is safe and easy to implement in the OACs.This study was conducted with the patients, who required the treatment of the OAC, which was developed after the posterior maxillary tooth extraction in the Dental and Maxillofacial Department of the Faculty of Dentistry in Adnan Menderes University.Plasma-rich fibrin membranes were inserted in layers into the tooth socket so that they covered the OAC. Then these membranes were fixated with the sutures to the surrounding gingiva. Antibiotic (amoxicillin/clavulanic acid 1000 mg), analgesic (dexketoprofen trometamol and/or paracetamol), and oral rinse (0.2% chlorhexidine digluconate) agents were prescribed to all patients. The patients were examined in the 3rd and 7th days and 2 months after the operation.All patients tolerated PRF perfectly, and the soft tissue recovery was completed without any problem. Full epithelization was observed in the defect area in all patients. The OAC did not relapse in any patient.Plasma-rich fibrin technique is a simple and effective method, which can be used in the treatment of OACs with a diameter of 5 mm or less with a low risk of complications.

Treatment of chronic oroantral fistula with platelet-rich fibrin clot and collagen membrane: a case report

“…In the study by Demetoglu et al, 12 no flap was raised, and only a PRF membrane was used to fix the OAF opening.…”

“…One such enhancement method involves the use of platelet-rich fibrin (PRF), which is a reliable procedure for extracting growth factors from the patient’s own blood without the use of additives. 12 Many growth factors, such as platelet-derived growth factor and transforming growth factor (TGF)-β, are released from PRF. Growth factors can increase vascularization, do not cause an immunological reaction or pose an infection hazard, and can enhance fibroblast proliferation.…”

Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration

“…PRF clots enhance wound closure and reduce pain and swelling compared to buccal advancement flap (104). In addition, PRF membrane could be used to manage OAC of size ≤ 5 mm (105). However, further standardized studies are required to shed the light in such promised application.…”

Tratamento de Fístula Buco-sinusal: proposta de abordagem

“…As técnicas cirúrgicas empregadas para o fechamento das comunicações vão desde o fechamento primário do alvéolo durante a exodontia até os retalhos pediculados, que podem ser palatinos ou vestibulares (utilizando ou não o corpo adiposo bucal e biomateriais) 1,3,4 .…”