Clostridium welchii septicotoxemia

Clostridium perfringens Bacteraemia following Normal Vaginal Delivery

“…While generally benign, this anaerobic bacterium can, in rare instances, precipitate postpartum bacteraemia, presenting a diagnostic challenge due to its infrequency. Smith et al reported recovering C. perfringens from 10 to 27% of genital tract cultures in aborting women, with sepsis manifesting in less than 1% of the cases [ 7 ]. The exploration of C. perfringens has seen notable advancements in the recent past, contributing valuable insights into its epidemiology, pathogenic mechanisms, and diagnostic approaches.…”

Clostridium welchii infection following amniocentesis: a case report and review of the literature

“…Other authors have suggested that Cl. welchii infection associated with haemolysis is also an indication for total abdominal hysterectomy (Fray et al, 1984;Patchell, 1978;Smith et al, 1971;Stone, 1971). Two cases of Clostridium welchii infection following amniocentesis have been reported in the literature (Hovav et al, 1995;Fray et al, 1984).…”

“…Severe Clostridium infection associated with haemolysis has been considered as an indication for total abdominal hysterectomy and bilateral salpingo -opherectomy (Fray et al, 1984;Patchell, 1978;Smith et al, 1971;Stone, 1971). We report a case of severe Clostridial infection following amniocentesis-the patient developed septicaemia, haemolysis, DIC, renal failure and pulmonary oedema, and was successfully managed conservatively.…”