Clostridium perfringens – epidemiological importance and diagnostics

Kozieł, Nina; Kukier, E.; Kwiatek, K.

doi:10.21521/mw.6161

Cited by 3 publications

(1 citation statement)

References 49 publications

(78 reference statements)

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“…Dotychczas opisano 20 toksyn Clostridium perfringers, które można podzielić na cztery główne kategorie -uszkadzające błonę komórkową, tworzące pory, toksyny wewnątrzkomórkowe oraz enzymy hydrolityczne. Szczepy Clostridium perfringers są podzielone na pięć podtypów -A-E. Jednak najbardziej rozpowszechniony jest podtyp A, który wywołuje zatrucia pokarmowe [20]. Z kolei w badaniu Horiego i wsp.…”

Section: Probiotyki a Rak Jelita Grubegounclassified

The use of probiotics in prevention and treatment of gastric and colorectal cancer

Kaźmierczak-Siedlecka¹,

Makarewicz²

2020

Farm Pol.

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The use of probiotics in prevention and treatment of gastric and colorectal cancer The composition of gut microbiota depends on many factors, such as age, life style (eating habits and the level of physical activity), pharmacological treatment (antibiotics, side effects of anti-cancer therapy) as well as surgical procedures. The gut microbiota is involved in carcinogenesis process. Furthermore, gut dysbiosis is described as qualitative and quantitative alterations in gut microbiota and it is observed in cancers. For instance, in patients with colorectal cancer the increased amount of Fusobacterium nucleatum, Bacteroides fragilis, Enterococcus faecalis, Streptococcus bovis as well as Peptostreptococcus anaerobius is noted. It was confirmed that amount of several specific bacteria, such as Lactobacillus, Escherichia-Shigella, Nitrospirae, Burkholderia fungorum and Lachnospiraceae, is increased in patients with gastric cancer. However, the major carcinogen involved in gastric carcinogenesis is Helicobacter pylori; it causes mucosa inflammation, mucosa atrophy, and as a consequence development of gastric cancer. Nowadays, there are several therapeutic methods, which may be used to alter the composition and the activity of gut microbiota. They include administration of probiotic strains, prebiotics, and synbiotics. Probiotics can be used to prevent the development of gastric and colorectal cancer, which was shown in many in vivo and in vitro studies. According to the most recent trials, probiotics reduce the incidence of diarrhoea associated with enteral nutrition. Probiotic strains may also be used as a supportive therapy in treatment of Helicobacter pylori infection. Notwithstanding, they can play a supportive role in standard eradication treatment due to reduction of adverse events of antibiotics. Probiotics decrease the incidence of infections in postooperative period, the frequency of abdominal pain, and radiation-induced diarrhoea. To sum up, probiotics may be used to prevent the development of cancer and they may significantly improve the efficiency of standard anti-cancer therapy.

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Section: Probiotyki a Rak Jelita Grubegounclassified

The use of probiotics in prevention and treatment of gastric and colorectal cancer

Kaźmierczak-Siedlecka¹,

Makarewicz²

2020

Farm Pol.

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Antimicrobial activity of selected plant extracts against common food borne pathogenic bacteria

Singh¹,

Naaz²,

Rakaseta³

et al. 2023

Food and Humanity

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Zakażenia przewodu pokarmowego w XXI wieku w Polsce i na świecie

Nowakowska

Demkow

Podsiadły

2021

Postępy Higieny I Medycyny Doświadczalnej

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At the beginning of the 21st century, there is still a global problem of gastrointestinal infections in all age groups of the population. Norovirus is considered the most common etiological factor of diarrheal disease transmitted by contaminated food in the world. The old etiological factor of diarrhoea such as Vibrio cholerae, Salmonella Typhi and Salmonella Paratyphi persist in the Western Pacific, in Southeast Asia, in the Eastern Mediterranean and in Africa. Children <5 years old are particularly sensitive to food-borne infections. Rotavirus is the primary etiological factor of diarrhoea in this age group in both developed and developing countries. Annually, 500 thousand deaths are reported in the world due gastroenteritis. Limited diagnostic standards of laboratory identification in Poland causes the epidemiological differences of the frequency of diarrheal enteropathogens compared to other countries; this applies to Campylobacter, Norovirus, Shigella. The dominant bacterial factor is Salmonella and among viral factors Rotavirus. In the 21st century knowledge about gastrointestinal infections can be reformulated and the list of etiological factors expanded. This idea is promoted by large-scale studies of intestinal microbiota and the application of new methods in routine diagnostics, such as mass spectrometry and real-time PCR.

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Clostridium perfringens – epidemiological importance and diagnostics

Cited by 3 publications

References 49 publications

The use of probiotics in prevention and treatment of gastric and colorectal cancer

The use of probiotics in prevention and treatment of gastric and colorectal cancer

Antimicrobial activity of selected plant extracts against common food borne pathogenic bacteria

Zakażenia przewodu pokarmowego w XXI wieku w Polsce i na świecie

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