Clostridium difficile and helicobacter pylori co-infection

Abstract

A 64 year old male patient presented with ulcerative colitis exacerbation along with dyspepsia, nausea and weight loss. He was found to have stool Clostridium Difficilis toxin test positive and H.Pylori stool antigen positive. It is rare to have both of these infections in the same patient and there is no guideline on management of this co infection. The plan was to start treatment of Clostridium Difficilis then to treat Helicobacter Pylori. The patient responded well to this management indicating the possibility of adopting this approach in such patients.

Treating Helicobacter pylori and Recurrent Clostridioides difficile Coinfection: A Delicate Balance in Management and a Need for Guidelines

“…The decision was made to treat the C. difficile before H. pylori infection, to which the patient responded well. 8 There are some limitations to the previously documented management strategies. In both reports, the patient did not experience acute complications from H. pylori that would otherwise prompt the need for acute management.…”