Clostridium aceticum—A potential organism in catalyzing carbon monoxide to acetic acid: Application of response surface methodology

Sim, Jia Huey; Kamaruddin, Azlina Harun; Long, Wei; Najafpour, Ghasem

doi:10.1016/j.enzmictec.2006.09.017

Cited by 69 publications

(27 citation statements)

References 11 publications

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“…Butanol production has been observed with Clostridium carboxidivorans and Butyribacterium methylotrophicum, while Clostridium drakei and Clostridium scatologenes are known to produce butyrate. In addition, the production of 2,3-butanediol has recently been reported for Clostridium ljungdahlii, Clostridium autoethanogenum and "Clostridium ragsdalei" [126].…”

Section: Organisms and Productsmentioning

confidence: 99%

“…Producing acetate from growth-supporting substrates including H 2 and CO 2 , CO and a range of sugars (fructose, ribose, glutamate, fumarate, malate and pyruvate), C. aceticum has an optimal growth temperature of 30 °C [136]. A genome sequence for the organism is currently under construction [46], and C. aceticum has recently been investigated for the production of acetic acid from synthesis gas [126], with a published productivity of 1.28 g L −1…”

Section: Acetate Producersmentioning

confidence: 99%

“…Used as a starting material for vinyl acetate and acetic anhydride synthesis [127], demand for acetic acid has grown over the past decade and is expected to reach 12.15 million tons by 2017 [128]. Three organisms have been used for acetate or calcium-magnesium-acetate (CMA) production: C. aceticum, M. thermoacetica and A. woodii [125,126,129,130].…”

Section: Acetate Producersmentioning

confidence: 99%

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Commercial Biomass Syngas Fermentation

2012

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Abstract:The use of gas fermentation for the production of low carbon biofuels such as ethanol or butanol from lignocellulosic biomass is an area currently undergoing intensive research and development, with the first commercial units expected to commence operation in the near future. In this process, biomass is first converted into carbon monoxide (CO) and hydrogen (H 2 )-rich synthesis gas (syngas) via gasification, and subsequently fermented to hydrocarbons by acetogenic bacteria. Several studies have been performed over the last few years to optimise both biomass gasification and syngas fermentation with significant progress being reported in both areas. While challenges associated with the scale-up and operation of this novel process remain, this strategy offers numerous advantages compared with established fermentation and purely thermochemical approaches to biofuel production in terms of feedstock flexibility and production cost. In recent times, metabolic engineering and synthetic biology techniques have been applied to gas fermenting organisms, paving the way for gases to be used as the feedstock for the commercial production of increasingly energy dense fuels and more valuable chemicals.

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Section: Organisms and Productsmentioning

confidence: 99%

Section: Acetate Producersmentioning

confidence: 99%

Section: Acetate Producersmentioning

confidence: 99%

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Commercial Biomass Syngas Fermentation

2012

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“…To indicate the accurate optimum point from the overlay plot, the independent factors and all the responses that were considered to be important were optimized simultaneously using the numerical optimization method in the Design Expert Software [19]. From the analysis, the highest efficiency of hydrogen production occurred at pH 5.86 and substrate concentration of 80 g/L which confirmed that the area for the optimum point was true.…”

Section: Effects Of Ph and Substrate Concentration On Hydrogen Producmentioning

confidence: 71%

Statistical Optimization of Biohydrogen Production from Palm Oil Mill Effluent by Natural Microflora

Rasdi¹,

Rahman²,

Abd‐Aziz³

et al. 2009

TOBIOTJ

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Abstract:In this study, palm oil mill effluent (POME) was used as the substrate for biohydrogen production. Heat-treated POME sludge acclimated with POME incubated at 37°C for 24 hours was used as seed culture. Preliminary screening on the effects of inocula sizes, heat treatment, substrate concentration and pH of incubation by using a factorial design (FD) were conducted under mesophilic condition (37°C) using a serum vial (160 mL). The experimental results from two-level FD showed that pH and Chemical Oxygen Demand (COD) of POME significantly affected biohydrogen production. Optimizations of the specific hydrogen production (P s ) and the hydrogen production rate (R m ) were achieved by using a central composite design (CCD). The maximum P s of 272 mL H 2 /g carbohydrate was obtained under optimum conditions of pH 5.75 and substrate concentration of 80 g/L. The maximum R m of 98 mL H 2 /h was calculated under the optimum conditions of pH 5.98 and substrate concentration of 80 g/L. The optimized conditions obtained were subjected to a confirmation run and it showed reproducible data with a P s of 226 mL H 2 /g carbohydrate and R m of 72 mL H 2 /h.

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“…20 Fatty acids can be generated directly from sugars by many fermentative bacteria, such as the members of genus Clostridium. 21 It was previously suggested that the fermentation metabolism may play different roles in MFCs. 22 -26 Firmicutes might serve the role of conversion of glucose into simple molecules and scavenging oxygen by their aerotolerant features for electrogenic microorganisms in glucose-fed MFCs.…”

Section: Production Of Vfasmentioning

confidence: 99%