Introduction: Rural populations routinely rank poorly on common health indicators including urologic cancer-specific mortality. While it is understood that rural residents face barriers to healthcare, the exact nature of these barriers has not been well described. In order to define these barriers, we performed a qualitative study to directly identify primary care physician perspective on healthcare access in rural areas. Methods: From January to August 2019, we conducted semi-structured interviews with 20 primary care physicians practicing in rural areas within western Pennsylvania. We purposively sampled primary care physicians in rural counties in Pennsylvania. We then recruited additional participants using a snowball recruitment strategy, in which the initial interviewees recommend other potential participants in their field. Data was then transcribed, coded, and analyzed via thematic analysis. Results: Participants identify the following as major healthcare barriers rural residents face: access to specialists, lack of transportation to medical centers, and financial burden. Financial barriers impact patients’ willingness to obtain screenings measures and attend specialist appointments secondary to co-pays. Primary care physicians report patients experience numerous hardships after being referred to a specialist, as they often have to travel long distances, lack means of transportation, are unwilling to skip work, have low healthcare literacy, and tend to be suspicious of medical treatment. Conclusion: Rural residents face numerous barriers to obtaining healthcare. Policy to rectify this disparity should focus on improving local access to care, transportation to tertiary care centers, and financial assistance for preventative screening measures.