Isolated closed subtalar joint dislocation is a very rare injury that accounts for only 1% of all joint dislocations. Subtalar joint dislocations are usually associated with fractures of the adjacent bones such as the calcaneus, malleolus, fifth metatarsal, or talus. The management of such cases is usually done as a closed reduction under general anesthesia. The use of regional anesthesia for such injuries has not been highlighted in the literature. In this case report, a patient presented with severe subtalar joint dislocation, which was managed with regional popliteal and saphenous nerve blocks. However, the closed reduction failed, and the surgeon proceeded with open reduction and internal fixation with no perioperative adverse events.